Special Issue "Recent Developments in Thyroid Hormone Regulation in Metabolic Diseases"
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 7935
Interests: physiologically relevant culture models; automated microscopes for cell monitoring; life cell imaging; biological assessment of nano and microparticles
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Today, thyroid diseases have become an interdisciplinary field of general practitioners, internists (endocrinologists, immunologists, oncologists), nuclear medicine specialists including radiation therapists, surgeons, ophthalmologists and other specialties. The use of modern technologies in basic research has enabled more insight into the mode of action of thyroid hormones and their metabolites, resulting in a potential therapeutic use of thyroid hormone metabolites.
One of the main tasks of thyroid hormones is to control important metabolic steps in the organism. Besides goiters with all their adverse effects on the organism, autoimmune diseases are among the most common thyroid diseases today. Abnormal thyroid hormones in particular have been linked to cardiovascular diseases, metabolic syndrome and cancer. This Special Issue aims to better understand the interplay of metabolic disorders and thyroid hormone metabolism, reveal new mechanisms of action and the regulation of thyroid hormones or their metabolites and identify innovative modalities for the treatment of thyroid diseases. The role of thyroid hormones and their metabolites in metabolic disorders, bile acid signaling, insulin sensitivity, hepatic gluconeogenesis, aging, neuro-modulatory effects and the immune system is still not entirely clear. Further, additional insight is needed into the regulation via the TRH–TSH–thyroid axis by nutritional signals.
We would like to encourage submissions (original articles, reviews, commentaries) on new findings related to normal and dysregulated thyroid metabolism.
Prof. Dr. Eleonore Fröhlich
Prof. Dr. Richard Wahl
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- T3, T4, TRH and TSH
- PPAR, liver X receptor
- bile acid
- insulin, insulin resistance, gluconeogenesis
- brown fat, white fat
- leptin, ghrelin
- inflammatory markers
- epigenetics and molecular biology
- bone metabolism
- cardiovascular effects