Role of Microbiome and Its Metabolites in Non-communicable Diseases

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Microbiology and Ecological Metabolomics".

Deadline for manuscript submissions: 31 March 2024 | Viewed by 163

Special Issue Editor

Human Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy
Interests: human microbiome; gut microbiome; microbial ecology; microbiome–host interaction; microbiome-based intervention; microbiome modulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The human gut microbiome has co-evolved with its host in a mutualistic relationship, providing key physiological functions aimed at maintaining the physiological state of health. Following the metabolism of dietary and/or host-derived compounds, the gut microbiome has the potential to produce a wide range of small bioactive molecules that exert a strong influence on multiple aspects of human physiology, from energy balance and metabolic regulation to the development and functioning of the immune, endocrine and nervous systems.

To date, multiple non-communicable diseases, such as metabolic syndrome, obesity, diabetes and cardiovascular and hepatic diseases, have been associated with impaired microbial layouts commonly known as dysbiosis.

Despite recent advances achieved through the integration of multi-omics data, the actual role of human microbiomes in the pathological context, possible causal relationships and underlying mechanisms have not yet been fully elucidated. In-depth studies of these aspects could help in developing increasingly effective and personalized microbiome-based intervention strategies, both for the prevention and treatment of non-communicable diseases.

This Special Issue aims to collect original articles and literature reviews focused on deepening knowledge on the mechanisms underlying the interaction between the microbiome and its metabolites on the health status of the host, with a particular focus on non-communicable diseases and the ways they can be modulated for the management or prevention of chronic conditions.

Dr. Monica Barone
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gut microbiota
  • non-communicable diseases
  • metabolic syndrome
  • obesity
  • diabetes
  • cardiovascular disease
  • microbial metabolites
  • microbial bioactive compounds
  • intervention strategies

Published Papers

This special issue is now open for submission.
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