Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.3
4.1
Journals
Metabolites
Special Issues
Significance of Plant Developmental Stages and Environmental Stress on Secondary...
share announcement

Significance of Plant Developmental Stages and Environmental Stress on Secondary Metabolites in Medicinal Plants

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Plant Metabolism".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 6099

Special Issue Editors

Dr. Supriya Tiwari

E-Mail Website
Guest Editor
Department of Botany, Institute of Science, Banaras Hindu University, Varanasi 221005, India
Interests: environmental stress; plant physiology; plant response to environmental stress
Prof. Dr. Shashi Bhushan Agrawal

E-Mail Website
Guest Editor
Department of Botany, Institute of Science, Banaras Hindu University, Varanasi 221005, India
Interests: environmental physiology; plant ecology; climate change; eco-physiology

Special Issue Information

Dear Colleagues,

Secondary metabolites (SMs) in plants are of paramount significance as they not only act as a defensive shield against stress but also act as signaling molecules in a number of plant processes. SMs are the main compounds of consideration in medicinal plants’ applications and are important components of pharmaceutical drugs as well as herbal remedies. SM production in plants is regulated by a number of factors, such as the species, genotype, cell type, developmental stage, environmental variations, etc. Different plant parts may produce distinctive SMs with characteristic medicinal properties at different developmental stages. As has been well-cited in the literature, plant development is highly susceptible to environmental stresses, and SM regulation is tightly linked to the environmental setup. In addition, various environmental stresses can bring about a direct alteration in the expression of genes involved in SM pathways.

This Special Issue explores the role of developmental processes under environmental stresses in the regulation of SMs in medicinal plants. This issue is intended to enrich our knowledge of SMs’ response in future climate change scenarios.

Dr. Supriya Tiwari
Prof. Dr. Shashi Bhushan Agrawal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • secondary metabolites
  • medicinal plants
  • development
  • stress
  • climate change

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

24 pages, 3949 KiB  
Article
Role of Elevated Ozone on Development and Metabolite Contents of Lemongrass [Cymbopogon flexuosus (Steud.) (Wats.)]
by Parvati Madheshiya, Gereraj Sen Gupta, Ansuman Sahoo and Supriya Tiwari
Metabolites 2023, 13(5), 597; https://doi.org/10.3390/metabo13050597 - 27 Apr 2023
Viewed by 1290
Abstract
The present study was conducted to assess the effect of elevated ozone stress on the development and metabolite contents of lemongrass, a medicinal plant. The experimental plant was exposed to two elevated ozone concentrations (ambient + 15 ppb, and ambient + 30 ppb) [...] Read more.
The present study was conducted to assess the effect of elevated ozone stress on the development and metabolite contents of lemongrass, a medicinal plant. The experimental plant was exposed to two elevated ozone concentrations (ambient + 15 ppb, and ambient + 30 ppb) using open-top chambers. Samplings were carried out at 45 and 90 days after transplantation (DAT), for the analysis of different characteristics, while the metabolite contents of leaves and essential oils were analyzed at 110 DAT. Both the doses of elevated ozone had notable negative effects on the carbon fixation efficiency of plants, resulting in a significant reduction in plant biomass. Enzymatic antioxidant activity increased during the second sampling, which suggests that the scavenging of reactive oxygen species was more prominent in lemongrass during the later developmental stage. The results of the present study showed a stimulated diversion of resources towards the phenylpropanoid pathway, which is made evident by the increase in the number and contents of metabolites in foliar extract and essential oils of plants grown at elevated ozone doses, as compared to ambient ozone. Elevated ozone not only upregulated the contents of medicinally important components of lemongrass, it also induced the formation of some pharmaceutically active bio compounds. On the basis of this study, it is expected that increasing ozone concentrations in near future will enhance the medicinal value of lemongrass. However, more experiments are required to validate these findings. Full article
(This article belongs to the Special Issue Significance of Plant Developmental Stages and Environmental Stress on Secondary Metabolites in Medicinal Plants)
►▼ Show Figures

Figure 1

16 pages, 3252 KiB  
Article
Metabolomics-Based Analysis of the Effects of Different Cultivation Strategies on Metabolites of Dendrobium officinale Kimura et Migo
by Da Yang, Yeyang Song, Anjin Lu, Lin Qin, Daopeng Tan, Qianru Zhang, Yuqi He and Yanliu Lu
Metabolites 2023, 13(3), 389; https://doi.org/10.3390/metabo13030389 - 06 Mar 2023
Cited by 2 | Viewed by 1411
Abstract
Dendrobium officinale Kimura et Migo is a famous plant with a high medicinal value which has been recorded in the Chinese Pharmacopoeia (2020 Edition). The medicinal properties of D. officinale are based on its chemical composition. However, there are no reports on how [...] Read more.
Dendrobium officinale Kimura et Migo is a famous plant with a high medicinal value which has been recorded in the Chinese Pharmacopoeia (2020 Edition). The medicinal properties of D. officinale are based on its chemical composition. However, there are no reports on how different cultivation methods affect its chemical composition. In order to reveal this issue, samples of the D. officinale were collected in this study through tree epiphytic cultivation, stone epiphytic cultivation, and greenhouse cultivation. Polysaccharides were determined by phenol sulfuric acid method and secondary metabolites were detected by the UPLC-MS technique. In addition, with regards to metabolomics, we used multivariate analyses including principal component analysis (PCA) and orthogonal partial least squares analysis (OPLS-DA) to screen for differential metabolites which met the conditions of variable importance projection values >1, fold change >4, and p < 0.05. The differential metabolites were taken further for metabolic pathway enrichment analysis, which was based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, and validated by antioxidant activity. Comparing the three groups of samples according to the standards of the ChP (2020 edition), the results showed that the polysaccharide content of the samples from stony epiphytic cultivation and greenhouse cultivation was significantly higher than that of the samples from live tree epiphytic cultivation. Metabolomic analysis revealed that there were 185 differential metabolites among the 3 cultivation methods, with 99 of the differential metabolites being highest in the stone epiphytic cultivation. The results of the metabolic pathway enrichment analysis showed that the different cultivation strategies mainly effected four carbohydrate metabolic pathways, five secondary metabolite synthesis pathways, six amino acid metabolic pathways, one nucleotide metabolism pathway, three cofactor and vitamin metabolism pathways, and one translation pathway in genetic information processing. Furthermore, D. officinale from stone epiphytic cultivation which had the best antioxidant activity was implicated in differential metabolite production. This study revealed the effects of different cultivation methods on the chemical composition of D. officinale and also provided a reference for establishing the quality control standards to aid its development and utilization. Full article
(This article belongs to the Special Issue Significance of Plant Developmental Stages and Environmental Stress on Secondary Metabolites in Medicinal Plants)
►▼ Show Figures

Figure 1

Review

Jump to: Research

25 pages, 6665 KiB  
Review
Identification, Biological Function Profiling and Biosynthesis of Secondary Metabolites in Medicinal Orchids
by Kunqian Li, Fengju Wu, Mengzhu Chen, Zhihao Xiao, Ya Xu, Mengwei Xu, Jingyi Liu and Delin Xu
Metabolites 2023, 13(7), 829; https://doi.org/10.3390/metabo13070829 - 07 Jul 2023
Viewed by 1345
Abstract
The secondary metabolites present in medicinal orchids are diverse and possess a vast array of biological activities. They represent valuable raw materials for modern pharmaceuticals and clinical medicine and have tremendous potential for future development. A systematic collation of secondary metabolites’ composition and [...] Read more.
The secondary metabolites present in medicinal orchids are diverse and possess a vast array of biological activities. They represent valuable raw materials for modern pharmaceuticals and clinical medicine and have tremendous potential for future development. A systematic collation of secondary metabolites’ composition and a summary of the biological activities of medicinal orchids represent a crucial step in unlocking the potential of these valuable resources in drug development. Furthermore, such information can provide essential guidance for comprehensively analyzing the pharmacological and therapeutic mechanisms of these valuable herbs in traditional Chinese herbal medicine. This review article presents an overview of the types and main biological functions of the secondary metabolites found in medicinal orchids, as well as the conventional synthesis methods for these compounds. Our aim is to provide a useful reference for future research and the drug development of secondary metabolic products of medicinal orchids. Full article
(This article belongs to the Special Issue Significance of Plant Developmental Stages and Environmental Stress on Secondary Metabolites in Medicinal Plants)
►▼ Show Figures

Graphical abstract

19 pages, 1337 KiB  
Review
Ultraviolet-B and Heavy Metal-Induced Regulation of Secondary Metabolites in Medicinal Plants: A Review
by Avantika Pandey, Madhoolika Agrawal and Shashi Bhushan Agrawal
Metabolites 2023, 13(3), 341; https://doi.org/10.3390/metabo13030341 - 24 Feb 2023
Cited by 5 | Viewed by 1522
Abstract
Despite a rich history and economic importance, the potential of medicinal plants has not been fully explored under different abiotic stress conditions. Penetration of UV-B radiation and contamination of heavy metals are two important environmental stress for plants with remarkable influence on the [...] Read more.
Despite a rich history and economic importance, the potential of medicinal plants has not been fully explored under different abiotic stress conditions. Penetration of UV-B radiation and contamination of heavy metals are two important environmental stress for plants with remarkable influence on the defense-related and pharmaceutically important secondary metabolites of medicinal plants. UV-B and heavy metal contamination may become a critical issue that either positively or negatively affects the quality and quantity of secondary metabolites. Such effects may result from changes in the expression level of genes that encode the corresponding enzymes or the inactivation and/or stimulation of specific enzymes involved in the different biosynthetic pathways of the secondary metabolites. Therefore, a comprehensive study of the impact of UV-B and heavy metals individually and in combination on the biosynthesis and accumulation of secondary metabolites in medicinal plants is discussed in the present review. Full article
(This article belongs to the Special Issue Significance of Plant Developmental Stages and Environmental Stress on Secondary Metabolites in Medicinal Plants)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop