Role of Microbial Metabolites in the Regulation of Host Immunity and Metabolism
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Food Metabolomics".
Deadline for manuscript submissions: closed (15 March 2023) | Viewed by 7027
Special Issue Editor
Special Issue Information
Dear Colleagues,
Balance among various physiological functions is important to maintain a state of good health. Among the various physiological functions, metabolism and immunity play key roles in regulating energy and protecting us from health threats. For a long time, it was thought that genes are the major players in this process. However, with time we learned that we have resident microbes (overtly bacteria, but also viruses and fungi) that are either equal or greater in number than the host cells. In addition, the metagenome (the genome of the resident microbes) number is at least a couple of logs higher than the host’s. Naturally, it was thought that the resident microbes, and especially the gut (the organ that populates most of the microbes) bacteriome (which is greater in number than other microbes) would play critical roles in maintaining physiological balance or homeostasis to keep the host healthy. In general, these microbes help to digest foods that the host would otherwise find difficult or impossible to digest. These difficult to digest foods are processed by the microbes to produce meta-metabolites or molecules such as short-chain fatty acids, in order to provide immune protection to the host. The microbiome could also regulate energy utilization and the host metabolism. The focus of the current issue is to understand how the meta-metabolites or microbial metabolites regulate host metabolism and immunity. We are open to accepting original research articles, reviews, and mini reviews.
Prof. Dr. Palok Aich
Guest Editor
Manuscript Submission Information
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Keywords
- metabolites and metabolism
- microbiome
- metagenomics
- pathways and networks
- immunity
