Dear Colleagues,

Plant metabolites are active chemical compounds derived naturally from primary plant metabolic pathways. Such phytochemicals are not essential for plant growth and propagation but possess a vital role in plant interaction with biotic and abiotic factors of their ecosystem. In the present era of phytopharmaceutical product development, there is a tremendous increase in the use of phytochemicals. These metabolites can be grouped based on their chemical structure that includes phenolic compounds, organic acids, glucosinolates, cyanogenic glucosides, amines, non-protein amino acids, peptides, alkaloids, and terpenes. Metabolites are commercially interesting, and they are currently exploited in several fields, such as in the production of ordinary food, novel food, cosmetics, agrochemicals, fine chemicals, biopharmaceuticals, and nutraceuticals. Several studies on plant metabolites have revealed their applications in antibacterial, antifungal, chemopreventive, anti-inflammatory, antidiabetic, anti-angiogenic activities, etc. and have made researchers focus more on plant-derived drug developments to fight against malignant disorders. As key compounds in diet, they can promote healthy life with their antioxidative properties. Despite the availability of synthetic medicine for these diseases, however, the chemicals used in them come with various side effects.

In this Special Issue, in addition to review articles, we invite original articles that deal with ideas related to plant-derived products with antibacterial, anticancerous, antifungal and any other properties, as well as novel toxicological studies and preclinical trials on different flavonoids.

Dr. Mallappa Kumara Swamy
Dr. Natesan Karthi
Dr. Bala Murali Krishna Vasamsetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• metabolites
• flavonoids
• antibacterial
• antifungal
• anticancer
• toxicity
• pharmaceutical activity
• transcriptome