Lipidomic Signatures in Pediatric Metabolic Disorders

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Lipid Metabolism".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 142

Special Issue Editor


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Guest Editor
Division of Pathology and Laboratory Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
Interests: lipidomics; metabolomics; bile acids; mass spectrometry; liquid chromatography; gas chromatography; pediatric metabolic disorders; statistics

Special Issue Information

Dear Colleagues,

Lipids play critical roles in structural compartmentalization (barrier function), energy storage, and signal transduction, serving as key pathophysiological mediators that regulate intracellular functions, comprising apoptosis, inflammation, proliferation, and response to stress. Today, dyslipidemia is associated with multiple congenital metabolic diseases with multidisciplinary clinical appearances, including ophthalmological, neurological, renal, dermatological, orthopedic, skeletal, immune, and hepatic presentations. New lipidomic technologies and studies will allow for the identification of rare diseases in the next few years.

In recent years, different pathologies have been raised in children in industrialized countries, making the pediatric population the subject of new lines of research for understanding subsequent treatment options for providing patients with a better quality of life in the future. Some of the studied pathologies are diabetes, non-alcoholic fatty liver, and obesity. Lifestyle and dietary changes are influencing the development of these pathologies. However, other rare metabolic disorders that could not be considered in previous years are also being studied, though their metabolic pathways could be assessed based on the recent advances in analytical techniques, such as lipidomic analysis performed via mass spectrometry.

The scope of this Special Issue “Lipidomic Signatures in Pediatric Metabolic Disorders” covers topics that include lipidomic studies of the pediatric population, which can comprise, but are not limited to, new analyses, profiling, and therapies that affect and involve lipids.     

Dr. Mónica Narváez-Rivas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lipidomics
  • lipids
  • mass spectrometry
  • pediatric population
  • therapeutic targets
  • biomarkers
  • metabolic disorder

Published Papers

This special issue is now open for submission.
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