Polycystic Ovary Syndrome
Deadline for manuscript submissions: closed (30 May 2019) | Viewed by 77678
Interests: androgens; female fertility; PCOS
Polycystic ovary syndrome (PCOS) affects >100 million women worldwide and is characterized by reproductive, metabolic, and endocrine disturbances. In addition, mounting evidence from human and animal studies implies that adverse PCOS health traits can be transferred to offspring. The high prevalence and wide range of adverse health conditions associated with PCOS brings an urgent challenge—to address not only the infertility, but also to ameliorate the metabolic disorders and intergenerational transmission of PCOS-related ill-health. Recent advances have included consensus international evidence-based guidelines for the assessment and management of PCOS aiming to unify and improve the care and health of women with PCOS. However, as the origin of PCOS remains unknown, there is neither cure nor specific treatment. Hence, there is a pressing need to develop targeted evidence-based treatments for PCOS, but this requires a much deeper knowledge of the physiological mechanisms underpinning its evolution.
This Special Issue will feature short, focused reviews discussing the distinctive features and comorbidities associates with PCOS, the modern evidence-based clinical assessment and management of PCOS, lessons learned from PCOS animal models, and the latest novel ideas in the pathophysiology of PCOS. This Special Issue aims to provide an update on advances and challenges in the field of PCOS. The goal is to provide up-to-date information on new and developing ideas on the origins, diagnosis, and management of PCOS, highlighting the latest concepts in understanding the etiology of PCOS, while also generating thought-provoking directions for future investigations and management.
Dr. Kirsty Walters
Prof. David Handelsman
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