Feature Papers

A special issue of Medicines (ISSN 2305-6320).

Deadline for manuscript submissions: closed (30 May 2015) | Viewed by 28770

Special Issue Editor

High-Tech Acupuncture and Digital Chinese Medicine, Swiss University of Traditional Chinese Medicine, 5330 Bad Zurzach, Switzerland
Interests: photobiomodulation; laser therapy; laser acupuncture; laser medicine; evidence-based complementary medicine
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Special Issue Information

Dear Colleagues,

Medicines is an international open-access journal of conventional medicine and proven or evidence-based traditional, complementary and alternative medicine, published quarterly online.

This Special Issue focuses on the latest innovative aspects that underline the further enhancement and development of medicine. Special emphasis is given to new methodological and technical investigations, for example, results obtained from all kinds of innovations in the field of integrative medicine.

We welcome papers reporting the latest results of evidence-based complementary medicine and those exploring integrative medicine in general. Studies concerning biomedicine based on modern technology are especially welcome. Manuscripts should deal with, but are not limited to, the keywords listed below.

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Prof. Dr. Gerhard Litscher
Guest Editor

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Keywords

  • evidence-based complementary medicine
  • integrative medicine
  • traditional medicine
  • acupuncture
  • herbal medicine
  • laser medicine

Published Papers (5 papers)

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Research

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453 KiB  
Article
The Potential of Double Blinding with Two Placebo Acupuncture Needles: A Randomized Controlled Pilot-Trial
by Miho Takayama, Hiroyoshi Yajima, Akiko Kawase, Ikuo Homma, Masahiko Izumizaki and Nobuari Takakura
Medicines 2015, 2(1), 11-27; https://doi.org/10.3390/medicines2010011 - 30 Dec 2014
Cited by 5 | Viewed by 6109
Abstract
Background: Whether acupuncture treatment employing multiple penetrating, skin-touch placebo, or no-touch placebo needles designed for double blinding actually do blind practitioners and patients has not been investigated. We aimed to investigate this question. Subjects: 120 patients with functional neck/shoulder stiffness but in otherwise [...] Read more.
Background: Whether acupuncture treatment employing multiple penetrating, skin-touch placebo, or no-touch placebo needles designed for double blinding actually do blind practitioners and patients has not been investigated. We aimed to investigate this question. Subjects: 120 patients with functional neck/shoulder stiffness but in otherwise healthy condition were randomly assigned to a treatment using four penetrating, four skin-touch placebo, or four no-touch placebo needles. Each of six acupuncturists applied four needles to four acupoints in the neck/shoulder of 20 patients. Acupuncturists and patients were asked to guess the treatment mode and their confidence in their guesses on 100 mm visual analog scales. Results: The kappa coefficients between practitioner guesses and treatment type and between patient guesses and treatment type were 0.15 and 0.44, respectively. The median score of practitioner confidence was 46.8, and no significant difference in confidence between correct and incorrect guesses was revealed for any treatment. The median score of patient confidence for correct guesses was 77.6. The kappa coefficient between practitioner and patient guesses was 0.06. Conclusions: The practitioners were blinded to the nature of treatment using the same multiple needles, but patient blinding was insufficient. Further improvement is necessary to achieve satisfactory patient blinding with these acupuncture needles. Full article
(This article belongs to the Special Issue Feature Papers)
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758 KiB  
Article
RegentK and Physiotherapy—Electrodermal Mapping
by Gerhard Litscher, Daniela Litscher, Michael Ofner, Ingrid Gaischek and Daniela-Eugenia Malliga
Medicines 2014, 1(1), 22-31; https://doi.org/10.3390/medicines1010022 - 30 Sep 2014
Cited by 3 | Viewed by 5346
Abstract
Background: Within this study, a new system which measures and analyzes electrical skin impedance in 48 channels within a 2.5 × 3.5 cm matrix is used in rehabilitation medicine for the first time. Methods: Electrodermal activity was measured in 20 patients before and [...] Read more.
Background: Within this study, a new system which measures and analyzes electrical skin impedance in 48 channels within a 2.5 × 3.5 cm matrix is used in rehabilitation medicine for the first time. Methods: Electrodermal activity was measured in 20 patients before and after two different non-surgical treatments of a completely ruptured anterior cruciate ligament. The first treatment, RegentK, was developed by Mohamed Khalifa, the second is a standard physiotherapy. Results: The patients in the two groups were age-matched, and all demographic data showed no significant differences. It was interesting that electrodermal activity was significantly decreased only after RegentK. Conclusion: We conclude that not only local effects of pressure application are responsible for these results, rather as yet unknown neurovegetative mechanisms have to be taken into consideration. Full article
(This article belongs to the Special Issue Feature Papers)
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1034 KiB  
Article
Temperature Measurements in Rehabilitation in Patients with Completely Ruptured Anterior Cruciate Ligament before and after RegentK and Physiotherapy
by Gerhard Litscher, Daniela Litscher, Michael Ofner, Ingrid Gaischek and Daniela-Eugenia Malliga
Medicines 2014, 1(1), 12-21; https://doi.org/10.3390/medicines1010012 - 16 Jul 2014
Cited by 4 | Viewed by 5836
Abstract
Acute skin surface temperature effects on the knee were investigated after a manual therapy developed by Mohamed Khalifa (RegentK) compared to standard physiotherapy in patients with completely ruptured anterior cruciate ligament (ACL). Twenty patients participated in this study. They were randomly assigned to [...] Read more.
Acute skin surface temperature effects on the knee were investigated after a manual therapy developed by Mohamed Khalifa (RegentK) compared to standard physiotherapy in patients with completely ruptured anterior cruciate ligament (ACL). Twenty patients participated in this study. They were randomly assigned to group A (receiving RegentK) or group B (physiotherapy). Each group consisted of 10 patients. Temperature values were registered on four spots (three on the knee, one on the foot) of the injured and the healthy leg (control). Skin temperature increased significantly after RegentK on all sites of the injured leg, but after physiotherapy only the measurement spots on the knee showed significant increases. After RegentK the temperature had also increased significantly on the control leg, whereas in group B, the results were not significant. Experimental and clinical testing of technical equipment, e.g., infrared thermography, for ACL injuries is important for a better understanding of the different physiological/pathophysiological mechanisms underlying different therapy approaches. Full article
(This article belongs to the Special Issue Feature Papers)
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398 KiB  
Article
Comparison of Cultivars and Seasonal Variation in Blueberry (Vaccinium Species) Leaf Extract on Adult T-Cell Leukemia Cell Line Growth Suppression
by Hisahiro Kai, Takuichi Fuse, Hisato Kunitake, Kazuhiro Morishita and Koji Matsuno
Medicines 2014, 1(1), 3-11; https://doi.org/10.3390/medicines1010003 - 30 Jun 2014
Cited by 12 | Viewed by 5446
Abstract
The inhibitory effects of blueberry leaves on the proliferation of adult T-cell leukemia (ATL) cell lines have previously been reported. A comparison of blueberry leaf extracts from different cultivars and seasonal variation were investigated regarding their effects on ATL cell line proliferation. The [...] Read more.
The inhibitory effects of blueberry leaves on the proliferation of adult T-cell leukemia (ATL) cell lines have previously been reported. A comparison of blueberry leaf extracts from different cultivars and seasonal variation were investigated regarding their effects on ATL cell line proliferation. The inhibitory effects of 80% ethanol leaf extracts from different blueberry cultivars collected from April to December in 2006 or 2008 were evaluated using two ATL cell lines. The bioactivities of leaf extracts of rabbit-eye blueberry (Vaccinium virgatum Aiton; RB species), southern highbush blueberry (V. spp.; SB species), northern highbush blueberry (V. corymbosum L.; NB species), and wild blueberry (V. bracteatum Thunb.; WB species) were compared. Of these, leaves of the RB species collected in December showed a significantly stronger inhibitory effect in both cell lines than the SB, NB, or WB species. These results suggest elevated biosynthesis of ATL-preventative bioactive compounds in the leaves of the RB species before the defoliation season. Full article
(This article belongs to the Special Issue Feature Papers)
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Review

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112 KiB  
Review
Acupoint Activation: Response in Microcirculation and the Role of Mast Cells
by Guangjun Wang, Daniela Litscher, Yuying Tian, Ingrid Gaischek, Shuyong Jia, Lu Wang, Weibo Zhang and Gerhard Litscher
Medicines 2014, 1(1), 56-63; https://doi.org/10.3390/medicines1010056 - 20 Nov 2014
Cited by 8 | Viewed by 5407
Abstract
Background: According to Traditional Chinese Medicine (TCM) theory, acupuncture effects are based on the integrity function of meridians. Meridians are thought to regulate body function through the normal flow of qi and/or blood. Disturbances in this flow are thought to cause disease, and [...] Read more.
Background: According to Traditional Chinese Medicine (TCM) theory, acupuncture effects are based on the integrity function of meridians. Meridians are thought to regulate body function through the normal flow of qi and/or blood. Disturbances in this flow are thought to cause disease, and acupuncture techniques are believed to cure disease by regulating this flow. However, it is still difficult to understand the exact meaning of qi and to evaluate the activation of meridians. Thus, more and more attention has been focused on the relationship of acupuncture and circulation. Methods: In this narrative review, the authors focus on the state of the art in acupoint activation, microcirculation response, and on investigation of mast cells, based on current literature research. Results: Altogether, 52 references are cited and discussed critically. A schematic diagram of the relationship between acupuncture stimulation, changes of microcirculation and mast cells is presented as result. Conclusion: The block diagram presented in this review article shows that mast cells might play an important role in circulation response after acupoint stimulation. Full article
(This article belongs to the Special Issue Feature Papers)
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