The Impact of Chemical Pollution on Human Health

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Epidemiology & Public Health".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2427

Special Issue Editor


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Guest Editor
Department of Toxicology “Akademik Danilo Soldatović”, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
Interests: toxicology; public health; PBDE; cadmium; human health; pollution; green; plastic; chemicals; endocrine disrupting; bisphenol A

Special Issue Information

Dear Colleagues,

Chemical pollution could have adverse effects on human health, including causing cancer, endocrine disruption, neurotoxicity, reproductive toxicity, etc. This Special Issue addresses the global public health concerns related to chemical pollution, including air, water, food, and soil pollution. It also addresses hazardous substances of global health concern such as toxic metals (cadmium, nickel, manganese, lead, and mercury), persistent organic pollutants (POPs), pesticides, and plasticizers such as phthalates and bisphenols, as well as major sources of their release and routes of exposure. Along with the adverse health effects observed in in silico, in vitro, and in vivo models, and from epidemiological studies, economic losses associated with exposure to the selected chemicals will be discussed. Eventually, attention should be paid to the chemical mixtures that simulate real-life exposure to these chemicals, their adverse health effects, and possible interactions.

Dr. Marijana Ćurčić
Guest Editor

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Keywords

  • chemicals
  • pollution
  • exposure
  • human health adverse effects
  • chemicals mixtures

Published Papers (1 paper)

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Research

11 pages, 1048 KiB  
Article
Knowledge on the Use of Isotretinoin and Its Side Effects and Awareness towards Saudi FDA-Pregnancy Prevention Program among the Female Acne Patients: A Northern Saudi Study
by Ziad Mansour Alshaalan
Medicina 2022, 58(11), 1609; https://doi.org/10.3390/medicina58111609 - 07 Nov 2022
Cited by 2 | Viewed by 2068
Abstract
Background and Objectives: Acne vulgaris is one of the most common dermatological disorders among adolescents and adults in the Kingdom of Saudi Arabia (KSA). Isotretinoin is a cost-effective way of treating severe acne patients compared to other methods used for severe forms of [...] Read more.
Background and Objectives: Acne vulgaris is one of the most common dermatological disorders among adolescents and adults in the Kingdom of Saudi Arabia (KSA). Isotretinoin is a cost-effective way of treating severe acne patients compared to other methods used for severe forms of acne management. The present study investigated the knowledge of the use of isotretinoin and its side effects among female acne patients of the reproductive age group who were on isotretinoin. This study also assessed participants’ awareness of the Saudi FDA-Pregnancy Prevention Program (SFDA-PPP). Materials and Methods: The present population-based cross-sectional survey was conducted among 768 participants using a standard and validated Arabic version questionnaire. We have applied logistic regression analysis to determine the predictors for awareness of SFDA-PPP. A Chi-square test was applied to identify the factors associated with knowledge related to isotretinoin. Results: Regarding the side effects of isotretinoin, participated female acne patients were most commonly aware of dry mouth and lips (84.5%), teratogenicity (68.2%), and headache (44.8%). Nearly 60% of the participants belonged to the low knowledge category. The present study participants’ knowledge was significantly associated with education status (p = 0.007), occupation (p = 0.01), and those participants who were aware of SFDA-PPP (p = 0.001). Furthermore, we explored that only 37.5% were aware of the SFDA-PPP program implemented in Saudi Arabia. The awareness of SFDA-PPP was significantly higher among those participants belonging to health sectors (Adjusted OR (95% CI) = 1.39 (1.01–1.92), p = 0.049). Conclusion: The present survey explored inadequate knowledge among reproductive age group female acne patients regarding isotretinoin uses, precautions to be followed, and side effects, especially teratogenic effects. This survey findings suggest that improving female acne patients’ knowledge of isotretinoin through health promotion activities is crucial, especially by giving them precise instructions about the teratogenic effects. Full article
(This article belongs to the Special Issue The Impact of Chemical Pollution on Human Health)
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