Special Issue "New Insights in Bleeding: From Diagnosis to Therapy"
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 7120
Interests: hemophilia; von willebrand disease; congenital hemorrhagic diseases; hypofibrinogenemia and dysfibrinogenemia; rare coagulation defects; replacement therapy; non-replacement therapy for hemophili
The term haemorrhage or bleeding refers to the sudden and intense leakage of blood from the blood vessels. Bleedings are distinguished according to the type of vessel involved, arterial or venous, and their location, external and internal. Their severity depends on the location of the bleeding, the amount of blood flowed and the accompanying symptoms, and it can lead to hemorrhagic shock and death if untreated. Bleeding is a common event, not only in patients with Congenital Hemorrhagic Disorders, and it can be caused by several accidents or conditions. Possible causes include:
Traumatic bleeding: an injury can cause traumatic bleeding. Common types of traumatic injuries include: abrasions that do not penetrate under the skin; hematoma or bruises; lacerations or incisions; injuries from objects such as needles or knives; crush injuries; gunshot wounds;
Medical Conditions: some medical conditions can cause bleeding. Haemorrhage due to a medical condition is less common than traumatic bleeding. Conditions that can cause it include: haematological disease; liver disease; menorrhagia; heavy or prolonged menstrual bleeding; thrombocytopenia; vitamin K deficiency; bowel obstruction; congestive heart failure; tumours; severe hypothermia;
Drugs: some medications can increase the risk of bleeding or even cause it. Drugs that may be responsible include: anticoagulants, antiplatelet agents; anti-inflammatories; antibiotics; radiotherapy; chemotherapy.
In addition, knowledge of bleeding causes plays a pivotal role in the choice of therapeutic options. Haemorrhages may be self-limiting, stopped by external pressure, or require IR or surgery to control. Medical management, surgery or endovascular treatment are the main strategies that can be adopted in case of bleeding. The total time needed to stop the haemorrhage critically affects outcomes. Endovascular treatment options are minimally invasive, cost-effective, and life-saving. A variety of embolization techniques and embolic agents have been described. Imaging should be performed before radiologic or operative intervention in patients who respond at least partially to resuscitation. Patients with ongoing hemodynamic instability that does not respond at least partially to adequate resuscitation may require immediate intervention.
This issue highlights recent advances in diagnostic and therapeutic options for bleeding.
We welcome articles providing new insights into the diagnosis and treatment of bleedings. We will be pleased to evaluate your interventional or observational studies evaluating the safety, effectiveness, and efficacy of new diagnostic tools and therapeutic options in bleeding patients.
Dr. Rita Carlotta Santoro
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- replacement therapy
- endovascular treatments
- anticoagulation and adverse hemorrhagic events
- reverse therapy
- acquired haemorrhagic disorders
- bleedings in pregnancy