Dear Colleagues,

Biomedical engineering, which combines the knowledge of several aspects of medical and engineering fields, has received great attention from the scientific research and medical community in recent decades. Many clinicians have considered new simulation software to understand its use for the purposes of treatment optimisation and outcome prediction based on a patient-specific modelling approach. 

Specific clinical applications include the understanding of human pathologies and diseases; the advancement of medical healthcare; and the improvement of diagnosis, therapies, and clinical outcomes. Other applications are related to the sport field. The performance of athletes can be studied and improved using different numerical simulators. 

The development of numerical or hybrid (numerical-hydraulic) models may also help to reduce the number of tests in animals and possibly contribute to the improvement of their wellbeing. Finally, numerical models have been developed to study biological problems, such as stem cell therapy, treatment of tumours, wound healing and microfluidics and diffusion processes.

The use of simulation software based on numerical/hybrid models describing organ or cell behaviour is becoming more popular for educational purposes.

This Special Issue is focused on the numerical modelling of the complex problems in the field of biomechanical and biomedical engineering, which include but are not limited to:

• Cardiovascular mechanics;
• Interaction between the cardiovascular system and mechanical assist devices and/or mechanical ventilation;
• Computational biofluid dynamics;
• Clinical application of novel numerical algorithms to the biomedical engineering;
• The use of numerical simulation in education;
• Tissue and cell mechanics;
• Numerical methods applied to biomechanics;
• Computer-assisted surgery and fluid dynamics;
• Multiscale flow modelling (3D, 1D, and 0D models);
• Biomechanics in athletics;
• Movement analysis and biomechanics for endurance sports;
• Application and impact of numerical models for decision making in sport;
• Molecular and cell therapies.

As such, high-quality original research papers are welcome.

Prof. Dr. Claudio De Lazzari
Prof. Dr. Sivia Marconi
Guest Editors

Beatrice De Lazzari
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Mathematics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• numerical model
• numerical software
• e-learning
• 0D, 1D, and 3D model
• clinical environment
• hybrid model
• athletic performance
• biomechanics in athletics
• movement analysis
• computer assist surgery