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Cyclodextrins: Aged Materials for New Applications
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Cyclodextrins: Aged Materials for New Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (10 October 2023) | Viewed by 5266

Special Issue Editors

Prof. Dr. Francesco Trotta

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Guest Editor
Departement of Chemistry, University of Turin, Via Pietro Giuria 7, 10125 Turin, Italy
Interests: cyclodextrin modification and functionalization; cyclodextrin nanosponges preparation and applications; drug delivery systems; biopolymers; membrane technology
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Andrea Mele

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Guest Editor
Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, Italy
Interests: cyclodextring chemistry; structure and dynamics of cyclodextrins' inclusion complexes via NMR spectroscopy; cyclodextrin nanosponges and their applications; transport properties of solutes encapsulated in cyclodextrin polymers and related hydrogels; cyclodextrins' properties in ionic liquids and deep eutectic solvents
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Fabiana Quaglia

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Guest Editor
Drug Delivery Laboratory, Department of Pharmacy, University of Napoli Federico II, Via Domenico Montesano 49, 80131 Naples, Italy
Interests: developing engineered polymeric nanoplatforms to target solid tumors; overcoming lung barriers after pulmonary administration and promoting wound healing; development of technological solutions to deliver drug combinations; RNA and light-activated therapeutics
Dr. Adrián Matencio

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Guest Editor
Department of Chemistry, University of Turin, Via Pietro Giuria 7, 10125 Turin, Italy
Interests: food biotechnology; molecular encapsulation; cyclodextrin; cyclodextrin-based materials; chemical synthesis; bioactive compounds; drug delivery; enzymology; molecular docking
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

From the 4th to 7th September 2022 in Ascea (Italy), “The V International Summer School on Cyclodextrins, advances in cyclodextrin chemistry and applications” will be held, where graduate students, Ph.D. students, post-doc students, young and senior researchers interested in all the aspects of cyclodextrin chemistry and applications will share their knowledge and learn about this topic. Cyclic oligosaccharides, discovered by Antoine Villiers in 1891, have had great scientific repercussions; although, in the beginning, the main function of this ring was to encapsulate in its interior compounds that, due to size or interaction, were stabilized in its hydrophobic cavity. However, different researchers have been modifying them to overcome this limitation and reach different applications. This is why they have found a great reception in the current scientific field, with innumerable applications in fields as disparate as pharmacology, food, energy or nuclear science, with more than 21,500 publications in the last 10 years (ISI web of science). This Special Issue is about the current state-of-the-art of systems of cyclodextrin chemistry and application in different fields, providing useful dissemination of the latest information. The Special Issue covers several aspects, from synthesis and characterization to application.

Prof. Dr. Francesco Trotta
Prof. Dr. Andrea Mele
Prof. Dr. Fabiana Quaglia
Dr. Adrián Matencio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • application of natural cyclodextrin
  • synthesis of modified cyclodextrins
  • cyclodextrin-based polymers
  • cyclodextrin-based materials
  • cyclodextrins in drug delivery systems
  • cyclodextrins for environmental applications
  • cyclodextrins for food and packaging
  • cyclodextrins against viruses and microorganisms
  • cyclodextrins in innovative solvents
  • physical methods for cyclodextrin derivatives characterization

Published Papers (2 papers)

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Review

25 pages, 7104 KiB  
Review
Cyclodextrins for Lithium Batteries Applications
by Mohamed M. H. Desoky, Fabrizio Caldera, Valentina Brunella, Riccardo Ferrero, Gjylije Hoti and Francesco Trotta
Materials 2023, 16(16), 5540; https://doi.org/10.3390/ma16165540 - 09 Aug 2023
Cited by 4 | Viewed by 1765
Abstract
Due to their high energy and power density, lithium-ion batteries (LIBs) have gained popularity in response to the demand for effective energy storage solutions. The importance of the electrode architecture in determining battery performance highlights the demand for optimization. By developing useful organic [...] Read more.
Due to their high energy and power density, lithium-ion batteries (LIBs) have gained popularity in response to the demand for effective energy storage solutions. The importance of the electrode architecture in determining battery performance highlights the demand for optimization. By developing useful organic polymers, cyclodextrin architectures have been investigated to improve the performance of Li-based batteries. The macrocyclic oligosaccharides known as cyclodextrins (CDs) have relatively hydrophobic cavities that can enclose other molecules. There are many industries where this “host–guest” relationship has been found useful. The hydrogen bonding and suitable inner cavity diameter of CD have led to its selection as a lithium-ion diffusion channel. CDs have also been used as solid electrolytes for solid-state batteries and as separators and binders to ensure adhesion between electrode components. This review gives a general overview of CD-based materials and how they are used in battery components, highlighting their advantages. Full article
(This article belongs to the Special Issue Cyclodextrins: Aged Materials for New Applications)
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15 pages, 1953 KiB  
Review
Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions
by Thorsteinn Loftsson, Hákon Hrafn Sigurdsson and Phatsawee Jansook
Materials 2023, 16(6), 2223; https://doi.org/10.3390/ma16062223 - 10 Mar 2023
Cited by 12 | Viewed by 2700
Abstract
Cyclodextrins (CDs) are cyclic oligosaccharides that emerged as industrial excipients in the early 1970s and are currently found in at least 130 marketed pharmaceutical products, in addition to numerous other consumer products. Although CDs have been the subject of close to 100,000 publications [...] Read more.
Cyclodextrins (CDs) are cyclic oligosaccharides that emerged as industrial excipients in the early 1970s and are currently found in at least 130 marketed pharmaceutical products, in addition to numerous other consumer products. Although CDs have been the subject of close to 100,000 publications since their discovery, and although their structure and properties appear to be trivial, CDs are constantly surprising investigators by their unique physicochemical properties. In aqueous solutions, CDs are solubilizing complexing agents of poorly soluble drugs while they can also act as organic cosolvents like ethanol. CDs and their complexes self-assemble in aqueous solutions to form both nano- and microparticles. The nanoparticles have diameters that are well below the wavelength of visible light; thus, the solutions appear to be clear. However, the nanoparticles can result in erroneous conclusions and misinterpretations of experimental results. CDs can act as penetration enhancers, increasing drug permeation through lipophilic membranes, but they do so without affecting the membrane barrier. This review is an account of some of the unexpected results the authors have encountered during their studies of CDs as pharmaceutical excipients. Full article
(This article belongs to the Special Issue Cyclodextrins: Aged Materials for New Applications)
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