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Antimicrobial Provided Advanced Materials for Biomedical Engineering Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (10 June 2023) | Viewed by 1727

Special Issue Editors

Department of Pharmaceutical Biotechnologies, National Institute for Chemical Pharmaceutical Research and Development –ICCF, 112 Vitan Avenue, 031299 Bucharest, Romania
Interests: antimicrobials; (bio)polymers; nanoparticles; wound dressings; prosthetic materials; catheters; cardiac devices; transdermal patches; medical devices
Department of Pharmaceutical Biotechnologies, National Institute for Chemical Pharmaceutical Research and Development –ICCF, 112 Vitan Avenue, 031299 Bucharest, Romania
Interests: antimicrobials; (bio)polymers; nanoparticles; wound dressings; prosthetic materials; catheters; cardiac devices; transdermal patches; medical devices

Special Issue Information

Dear Colleagues,

During recent decades, tremendous research and development efforts have been made for medical applications of smart materials as potential medical devices  of external and internal use. Thus, burns and wounds, tissue reconstruction and regeneration, but also transdermal drug controlled-release are important therapeutic targets. Association of antimicrobial activity has been compulsory, or at least promoting their efficacy in many cases, especially having in view the increasing dangerous environment generated by the antibiotic resistant microorganisms.

This Special Issue will focus on such advanced materials provided with antimicrobial activity due to included specific active agents, usable in recalcitrant infected wounds healing, orthopedics (bone and cartilage regeneration), traumatology, dentistry and maxillofacial surgery, and cardiac devices. The antimicrobials will be directly therapeutic or preventing microbial contamination/fouling, sometimes formulated as nanoparticles, included in different functional biocompatible materials, frequently (bio)polymers. Their efficacy in vitro/in vivo will highlight the advantages of ensuring antimicrobial activity in accelerating the healing and tissue regeneration processes. The meeting of certain safety conditions, depending on the type of contacted tissue (surface damaged tissue, implant), related to a medical device outlook, are very welcome. Methods for antimicrobial characterization for such materials are particularly considered.

Dr. Misu Moscovici
Dr. Angela Casarica
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobials
  • (bio)polymers
  • nanoparticles
  • wound dressings
  • prosthetic materials
  • catheters
  • cardiac devices
  • transdermal patches
  • medical devices

Published Papers (1 paper)

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Research

14 pages, 4528 KiB  
Article
Antimicrobial Properties of CuO Particles Deposited on a Medical Mask
by Agnė Giedraitienė, Modestas Ruzauskas, Rita Šiugždinienė, Simona Tučkutė and Darius Milcius
Materials 2022, 15(22), 7896; https://doi.org/10.3390/ma15227896 - 08 Nov 2022
Cited by 4 | Viewed by 1089
Abstract
Medical face masks help to reduce the transmission of pathogens, however, the number of infections caused by antimicrobial-resistant pathogens continues to increase. The aim of this study was to investigate the antimicrobial effect of an experimental medical mask layer coated with copper oxide [...] Read more.
Medical face masks help to reduce the transmission of pathogens, however, the number of infections caused by antimicrobial-resistant pathogens continues to increase. The aim of this study was to investigate the antimicrobial effect of an experimental medical mask layer coated with copper oxide using an environmentally friendly non-thermal physical vapour deposition approach. Pure CuO nanoparticles were successfully deposited on the middle layer of a face mask. The particles were distributed in different size clusters (starting from less than 100 nm dots going up to about 1 µm cluster-like structures). The CuO clusters did not form uniform films, which could negatively influence airflow during use of the mask. We investigated the antimicrobial properties of the experimental mask layer coated with CuO NPs using 17 clinical and zoonotic strains of gram-negative, gram-positive, spore-forming bacteria and yeasts, during direct and indirect contact with the mask surface. The effectiveness of the coated mask layer depended on the deposition duration of CuO. The optimal time for deposition was 30 min, which ensured a bactericidal effect for both gram-positive and gram-negative bacteria, including antimicrobial-resistant strains, using 150 W power. The CuO NPs had little or no effect on Candida spp. yeasts. Full article
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