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Surface Functionalization of Dental Biomaterials
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Surface Functionalization of Dental Biomaterials

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (24 November 2021) | Viewed by 8284

Special Issue Editors

Prof. Dr. Guido Macchiarelli

E-Mail Website
Guest Editor
Department of Life, Health and Environmental Sciences, University of L’Aquila, L'Aquila, Italy
Interests: morphology; microscopy; SEM; TEM; biomaterials; dental sciences
Special Issues, Collections and Topics in MDPI journals
Dr. Sara Bernardi

E-Mail Website
Guest Editor
Department of Life Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy
Interests: anatomy; dentistry; anatomy teaching; innovation in education; oral surgery; regenerative dentistry; oral biofilm; biomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Research on dental biomaterials is constantly evolving to meet the demands of patients requiring a higher standard and quality of dental treatment. Dental therapies rely on the use of several materials with a high degree of biocompatibility and a wide range of applications, such as restorative dentistry, prosthodontics, orthodontics, and regenerative surgeries. A crucial aspect of biomaterials is represented by the interface with the biological tissue. Therefore, the surfaces are constantly studied as a way to achieve higher performing results.

The current Special Issue is focused on the delicate interface and functionalization of the surface of the materials used in the dental fields, aiming to advertise new discoveries and the potential of their clinical applications.

Full papers, communications, and reviews are all welcome in this Special Issue.

Prof. Guido Macchiarelli
Dr. Sara Bernardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biocompatibility
  • scaffold
  • jawbone regeneration
  • delivery biomaterials
  • resin composites
  • dentin derived biomaterials
  • autologous platelet concentrate
  • dental implants
  • prosthodontic materials

Published Papers (3 papers)

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Research

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12 pages, 7822 KiB  
Article
Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
by Jung-Gu Ji, Jung-A Yu, Seong-Ho Choi and Dong-Woon Lee
Materials 2021, 14(14), 3828; https://doi.org/10.3390/ma14143828 - 08 Jul 2021
Cited by 5 | Viewed by 1992
Abstract
Vertical ridge augmentation for long-term implant stability is difficult in severely resorbed areas. We examined the clinical, radiological, and histological outcomes of guided-bone regeneration using novel titanium-reinforced microporous expanded polytetrafluoroethylene (MP-ePTFE) membranes. Eighteen patients who underwent implant placement using a staged approach were [...] Read more.
Vertical ridge augmentation for long-term implant stability is difficult in severely resorbed areas. We examined the clinical, radiological, and histological outcomes of guided-bone regeneration using novel titanium-reinforced microporous expanded polytetrafluoroethylene (MP-ePTFE) membranes. Eighteen patients who underwent implant placement using a staged approach were enrolled (period: 2018–2019). Vertical ridge augmentation was performed in areas with vertical bone defects ≥4 mm. Twenty-six implant fixtures were placed in 14 patients. At implant placement six fixtures had relatively low stability. On cone-beam computed tomography, the average vertical changes were 4.2 ± 1.9 (buccal), 5.9 ± 2.7 (central), and 4.4 ± 2.8 mm (lingual) at six months after vertical ridge augmentation. Histomorphometric analyses revealed that the average proportions of new bone, residual bone substitute material, and soft tissue were 34.91 ± 11.61%, 7.16 ± 2.74%, and 57.93 ± 11.09%, respectively. Stable marginal bone levels were observed at 1-year post-loading. The residual bone graft material area was significantly lower in the exposed group (p = 0.003). There was no significant difference in the vertical height change in the buccal side between immediately after the augmentation procedure and the implant placement reentry time (p = 0.371). However, all implants functioned well regardless of the exposure during the observation period. Thus, vertical ridge augmentation around implants using titanium-reinforced MP-ePTFE membranes can be successful. Full article
(This article belongs to the Special Issue Surface Functionalization of Dental Biomaterials)
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12 pages, 3940 KiB  
Article
Histological and Histomorphometric Evaluation of New Bone Formation after Maxillary Sinus Augmentation with Two Different Osteoconductive Materials: A Randomized, Parallel, Double-Blind Clinical Trial
by Giuseppe Grasso, Stefano Mummolo, Sara Bernardi, Davide Pietropaoli, Giuseppe D’Ambrosio, Giovanna Iezzi, Adriano Piattelli, Serena Bianchi and Enrico Marchetti
Materials 2020, 13(23), 5520; https://doi.org/10.3390/ma13235520 - 03 Dec 2020
Cited by 30 | Viewed by 2144
Abstract
This study aimed to investigate the histological features of deproteinized equine bone mineral (DEBM) and anorganic bovine bone (ABB) after human sinus augmentation with the lateral approach. Twenty-three sinus augmentations were performed in 16 patients (male: 10/female: 6) using DEBM or ABB in [...] Read more.
This study aimed to investigate the histological features of deproteinized equine bone mineral (DEBM) and anorganic bovine bone (ABB) after human sinus augmentation with the lateral approach. Twenty-three sinus augmentations were performed in 16 patients (male: 10/female: 6) using DEBM or ABB in a randomized fashion. Healing took place over the next 6 months. Bone core biopsies (N = 23) were obtained for each subject prior to placing the dental implants. The biopsies were processed for both histological descriptions and histomorphometric analysis. Statistical analyses were applied as appropriate, defining statistical significance as p < 0.05. Core bone biopsies revealed no differences in terms of newly formed bone between groups, or differences in terms of tissue inflammation. Both DEBM and ABB appear to be suitable biomaterials for bone augmentation in sinus lift surgery in the short term. However, dedicated studies are required to confirm these results and their stability in the long term. Full article
(This article belongs to the Special Issue Surface Functionalization of Dental Biomaterials)
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Review

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20 pages, 3160 KiB  
Review
The Effects of Sterilization Procedures on the Cutting Efficiency of Endodontic Instruments: A Systematic Review and Network Meta-Analysis
by Mario Dioguardi, Enrica Laneve, Michele Di Cosola, Angela Pia Cazzolla, Diego Sovereto, Riccardo Aiuto, Luigi Laino, Teresa Leanza, Mario Alovisi, Giuseppe Troiano and Lorenzo Lo Muzio
Materials 2021, 14(6), 1559; https://doi.org/10.3390/ma14061559 - 22 Mar 2021
Cited by 9 | Viewed by 3396
Abstract
Sterilization processes guarantee the sterility of dental instruments but can negatively affect instrument features by altering their physical and mechanical properties. The endodontic instrumentation can undergo a series of alterations, ranging from corrosion to variation in the cutting angle and then changes in [...] Read more.
Sterilization processes guarantee the sterility of dental instruments but can negatively affect instrument features by altering their physical and mechanical properties. The endodontic instrumentation can undergo a series of alterations, ranging from corrosion to variation in the cutting angle and then changes in the torsional properties and torsional fatigue resistance. This systematic literature review and meta-analysis aims to investigate alterations to the cutting efficiency of endodontic instruments that are induced by procedures for their disinfection and sterilization. Methodologies adopted for this investigation follow the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines. The following were used as search terms on PubMed and Scopus: “endodontic sterilization”, “endodontic autoclave”, “cyclic fatigue”, “torsional”, “cutting efficiency”, “sterilization”, “surface characteristics”, and “corrosion”. At the end of the selection process, 36 articles were identified, and seven of them are included in this systematic review. The results of a meta-analysis conducted for the use of 10 autoclaving cycles shows a standardized mean difference (SMD) of 0.80 with a p-value equal to 0.04 with respect to effect on cutting efficiency. The network meta-analysis, through direct and indirect comparison between the different autoclave cycles (0, 1, 5, 10, and 15 cycles), revealed that treatment involving 15 autoclave cycles produced the most robust results in terms of having the greatest effects in terms of altered cutting efficiency with a probability of 57.7% and a SUCRA (surface under the cumulative ranking) of 80%. The alterations in the effects on cutting efficiency appear to be triggered after five cycles of sterilization by heat (autoclave). In conclusion, the meta-analysis of the data indicates that the autoclave sterilization protocol must not be repeated more than five times to preserve cutting efficiency. Within the limitations of this review, we can therefore establish that sterilization by autoclaving alone results in steel and NiTi instruments becoming less efficient in cutting after five cycles, as measured by a reduction in cutting efficiency. Full article
(This article belongs to the Special Issue Surface Functionalization of Dental Biomaterials)
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