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Synthetic/Nature Polymers in Bioengineering
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Synthetic/Nature Polymers in Bioengineering

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (10 June 2022) | Viewed by 2115

Special Issue Editor

Prof. Dr. Liliana Mititelu-Tartau

E-Mail Website
Guest Editor
Department of Pharmacology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
Interests: polymers; biocompatible; biodegradable; bioconjugates; nanoparticles; microparticles; drug delivery systems; biological targets; animal models
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, synthetic/nature polymers and polymeric assemblies have become important tools for biological sciences in interacting with biological moieties to improve the efficiency of therapeutics delivery, diagnostics, and biological assays.

For example, polymeric nanocomposites are used in the drug-carrier design, demonstrating their potential to be used in basic research and clinical medicine. Polymeric materials have distinguishing properties that make them widely used in a great variety of biomaterial applications in the medical and surgical fields, as well as drug delivery systems. Polymeric matrices serve as a vehicle to incorporate additives (flavor agents, colorants, antioxidants, antimicrobial substances). The development of new multifunctional materials through the addition of pharmacologic active agents is an innovative trend and main strategy in polymer science, with clear practical interest.

Innovative biocomposite formulations containing various compounds can complete the needs related to active packaging functions, such as food protection and preservation; new packaging characteristics such as improved mechanical, barrier, antioxidant, antimicrobial properties, and biological functions; protection to consumers’ health; marketing; smart communication to consumers; and environmental degradation, which can decrease pollution and generate a positive environmental impact and reduced waste generation.

In this Special Issue, we invite researchers to submit original research articles as well as review articles focusing on multiple issues about polymers, such as the obtaining, characterization, structure, and original aspects of polymeric matrix biocomposites for creating nanostructures; possibly revealing novel design technologies, advantages, disadvantages, and their various medical applications; harvesting, treatment & applications of natural polymers such as wool, silk or proteins.

Hot topics to be covered by the Special Issue include:

  • Composite materials with polymer matrices
  • Biocompatible polymers
  • Biomaterials
  • Nature polymers
  • Advanced technologies of composite materials manufacturing
  • Medical devices
  • Drug delivery
  • In vitro study
  • Biocompatibility evaluation
  • In vivo animal models
  • Various applications of polymeric matrix composites

Prof. Dr. Liliana Mititelu-Tartau
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymer-matrix
  • smart polymers
  • biocomposites
  • bio-hybrid systems
  • advanced technologies
  • drug delivery

Published Papers (1 paper)

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Research

20 pages, 5321 KiB  
Article
The Impact of the Matricaria chamomilla L. Extract, Starch Solution and the Photoinitiator on Physiochemical Properties of Acrylic Hydrogels
by Mateusz Jamroży, Magdalena Głąb, Sonia Kudłacik-Kramarczyk, Anna Drabczyk, Paweł Gajda and Bożena Tyliszczak
Materials 2022, 15(8), 2837; https://doi.org/10.3390/ma15082837 - 12 Apr 2022
Cited by 5 | Viewed by 1509
Abstract
Matricaria chamomilla L. extract is well-known for its therapeutic properties; thus, it shows potential to be used to modify materials designed for biomedical purposes. In this paper, acrylic hydrogels modified with this extract were prepared. The other modifier was starch introduced into the [...] Read more.
Matricaria chamomilla L. extract is well-known for its therapeutic properties; thus, it shows potential to be used to modify materials designed for biomedical purposes. In this paper, acrylic hydrogels modified with this extract were prepared. The other modifier was starch introduced into the hydrogel matrix in two forms: room-temperature solution and elevated-temperature solution. Such hydrogels were synthesized via UV radiation, while two types of photoinitiator were used: 2-hydroxy-2-methylpropiophenone or phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide. The main task of performed research was to verify the impact of particular modifiers and photoinitiator on physicochemical properties of hydrogels. Studies involved determining their swelling ability, elasticity, chemical structure via FTIR spectroscopy and surface morphology via the SEM technique. Incubation of hydrogels in simulated physiological liquids, studies on the release of chamomile extract from their matrix and their biological analysis via MTT assay were also performed. It was demonstrated that all investigated variables affected the physicochemical properties of hydrogels. The modification of hydrogels with chamomile extract reduced their absorbency, decreased their thermal stability and increased the cell viability incubated with this material by 15%. Next, hydrogels obtained by using phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide as a photoinitiator showed lower absorbency, more compact structure, better stability in SBF and a more effective release of chamomile extract compared to the materials prepared by using 2-hydroxy-2-methylpropiophenone. It was proved that, by applying adequate reagents, including both photoinitiator and modifiers, it is possible to obtain hydrogels with variable properties that will positively affect their application potential. Full article
(This article belongs to the Special Issue Synthetic/Nature Polymers in Bioengineering)
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