Journal Browser

Journal Browser

Special Issue "Novel Dental Implant Coatings for Better Implant-Bone Integration Properties"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 10 July 2023 | Viewed by 940

Special Issue Editor

Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia
Interests: theoretical modeling; quantum-chemical calculations; bioactive coating; surface functionalization; surface characterization; structure–property relationship in dental materials

Special Issue Information

Dear Colleagues,

In recent years, the development of new coatings for dental implants has seen great progress. A wide range of coating materials are being intensively researched, including bioactive inorganic materials such as calcium phosphates, hydroxyapatite, bioceramics and bioactive glasses. Surface modification of implants with organic coatings such as various extracellular matrix proteins (collagen, fibronectin, fibrinogen) has proven to be an effective approach to improving biocompatibility. A relatively new approach is bioactive hybrid inorganic–organic coatings, which can perform some unique functions. For example, hydroxyapatite has been improved with the addition of amino acids. Similarly, bioactive composites of glass and natural polymers (collagen, gelatin, silk fibroin, hyaluronic acid, chitosan, alginate and cellulose) enhance the mechanical properties of the final system, as well as its bioactivity and regenerative potential. In addition to all the recent studies on the subject, biomimetic coatings are increasingly becoming the focus of research.

Certain factors must be considered when selecting and using materials for biological applications, such as their mechanical behavior, their thermal and electrical conductivity, biostability, biocompatibility, biodegradability, permeability to body fluids, non-toxicity, and non-allergenicity. In addition, there is great interest in coatings for dental implants that initiate, promote, and accelerate the process of osseointegration. Although the advances in the novel biomaterials for coatings developed so far are remarkable, the search for new materials and manufacturing processes is not over yet. An integrated experimental–theoretical approach is of great benefit in elucidating the mechanism of coating formation on dental implant surfaces.

The aim of this Special Issue is to bring together original papers and comprehensive reviews that open new horizons in the field of dental implant coatings. The articles will cover various topics, including novel coating materials for dental implants, new methods of coating formation, characterization of functionalized implant surfaces, investigation of the coating mechanism, and the structural and functional connections between the functionalized implant and the surrounding bone tissue.

Dr. Ines Despotović
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • multifunctional dental coating materials and structures
  • coating formation methods
  • coating formation mechanism
  • theoretical modeling
  • surface characterization methods
  • mechanical behavior of coating materials
  • anticorrosion protection
  • biocompatibility
  • osteoinductivity
  • osseointegration

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:


Novel Strategy for Surface Modification of Titanium Implants towards the Improvement of Osseointegration Property and Antibiotic Local Delivery
Materials 2023, 16(7), 2755; - 29 Mar 2023
Viewed by 722
The topography and chemical composition modification of titanium (Ti) implants play a decisive role in improving biocompatibility and bioactivity, accelerating osseointegration, and, thus, determining clinical success. In spite of the development of surface modification strategies, bacterial contamination is a common cause of failure. [...] Read more.
The topography and chemical composition modification of titanium (Ti) implants play a decisive role in improving biocompatibility and bioactivity, accelerating osseointegration, and, thus, determining clinical success. In spite of the development of surface modification strategies, bacterial contamination is a common cause of failure. The use of systemic antibiotic therapy does not guarantee action at the contaminated site. In this work, we proposed a surface treatment for Ti implants that aim to improve their osseointegration and reduce bacterial colonization in surgery sites due to the local release of antibiotic. The Ti discs were hydrothermally treated with 3M NaOH solution to form a nanostructured layer of titanate on the Ti surface. Metronidazole was impregnated on these nanostructured surfaces to enable its local release. The samples were coated with poly(vinyl alcohol)—PVA films with different thickness to evaluate a possible control of drug release. Gamma irradiation was used to crosslink the polymer chains to achieve hydrogel layer formation and to sterilize the samples. The samples were characterized by XRD, SEM, FTIR, contact angle measurements, “in vitro” bioactivity, and drug release analysis. The alkaline hydrothermal treatment successfully produced intertwined, web-like nanostructures on the Ti surface, providing wettability and bioactivity to the Ti samples (Ti + TTNT samples). Metronidazole was successfully loaded and released from the Ti + TTNT samples coated or not with PVA. Although the polymeric film acted as a physical barrier to drug delivery, all groups reached the minimum inhibitory concentration for anaerobic bacteria. Thus, the surface modification method presented is a potential approach to improve the osseointegration of Ti implants and to associate local drug delivery with dental implants, preventing early infections and bone failure. Full article
Show Figures

Figure 1

Back to TopTop