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Special Issue "Advances in Bionanocomposites for Biomedical Engineering"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 10 January 2024 | Viewed by 1696

Special Issue Editors

Bio-Interface & Environmental Engineering Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India
Interests: biointerfaces and biomaterials; protein adsorption and aggregation; nanomaterials and composites; environment biotechnology
Department of Biomedical Engineering, Military Institute of Science and Technology (MIST), Dhaka, Bangladesh
Interests: biomaterials; biocomposites; biofabrication; biomechanics; biomedical implants; nanomaterials; nanocomposites; nanotechnology; rapid prototyping technology; rehabilitation engineering; stem cells; tissue engineering
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Central Department of Chemistry, Tribhuvan University, Kathmandu, Nepal
Interests: electrospun nanofibrous scaffolds; nanofiber-reinforced hydrogel scaffold for tissue engineering and drug delivery

Special Issue Information

Dear Colleagues,

Bionanocomposites are considered to be an important class of hybrid materials consisting in good part of biopolymers, which demonstrate wider applications including biomedical engineering. Such biodegradable materials have proven to be invaluable gifts to present and future generations thanks to modern science and technology. Natural polymers are preferred from an environmental standpoint, while nanocomposites own inherent properties such as biocompatibility, biodegradability, proper mechanical strength, as well as improved structural and functional properties. These properties encourage the use of nanocomposites for various biomedical applications because of their widespread potential and advantage over other traditional synthetic materials.

The development of nanocomposites with different chemistries and compositions is a fascinating area of research which has myriad applications in biomedical fields such as tissue engineering, injectable materials, drug carrier, biological sensing, three-dimensional printing, wound healing, bone tissue engineering, medical implants, etc. Accordingly, many scientific and industrial communities have focused on nanocomposites to develop some new products or substitute available materials.

For example, one area of intense research involves electrospinning for the production of bioresorbable composite nanofibrous scaffolds for tissue engineering applications. Nanocomposite hydrogels, another class of biomaterials, have attracted considerable research interest over the last few years to compensate for the drawbacks of hydrogels such as weakness, brittleness, biocompatibility, drug retaining, and so on.

This Special Issue on “Advances in Bionanocomposites for Biomedical Engineering” aims to cover recent advances in the development of any type of composite biomaterials, including (but not limited to) nanofiber, composite nanoparticles, composite nanohydrogel for fundamental research and clinical applications viz. tissue engineering, chemical and biological sensing, injectable materials, and drug or gene delivery.

Dr. Lalit Mohan Pandey
Prof. Dr. Md. Enamul Hoque
Dr. Mahesh Kumar Joshi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • bionanocomposites
  • biofabrication
  • biointerface
  • biomedical
  • biopolymers
  • engineered nanomaterials
  • implant biomaterials
  • regenerative medicine
  • tissue engineering
  • drug delivery

Published Papers (1 paper)

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11 pages, 3417 KiB  
Three-Dimensional PLGA Nanofiber-Based Microchip for High-Efficiency Cancer Cell Capture
Materials 2023, 16(8), 3065; - 13 Apr 2023
Viewed by 1077
A 3D network capture substrate based on poly(lactic-co-glycolic acid) (PLGA) nanofibers was studied and successfully used for high-efficiency cancer cell capture. The arc-shaped glass micropillars were prepared by chemical wet etching and soft lithography. PLGA nanofibers were coupled with micropillars by electrospinning. Given [...] Read more.
A 3D network capture substrate based on poly(lactic-co-glycolic acid) (PLGA) nanofibers was studied and successfully used for high-efficiency cancer cell capture. The arc-shaped glass micropillars were prepared by chemical wet etching and soft lithography. PLGA nanofibers were coupled with micropillars by electrospinning. Given the size effect of the microcolumn and PLGA nanofibers, a three-dimensional of micro-nanometer spatial network was prepared to form a network cell trapping substrate. After the modification of a specific anti-EpCAM antibody, MCF-7 cancer cells were captured successfully with a capture efficiency of 91%. Compared with the substrate composed of 2D nanofibers or nanoparticles, the developed 3D structure based on microcolumns and nanofibers had a greater contact probability between cells and the capture substrate, leading to a high capture efficiency. Cell capture based on this method can provide technical support for rare cells in peripheral blood detection, such as circulating tumor cells and circulating fetal nucleated red cells. Full article
(This article belongs to the Special Issue Advances in Bionanocomposites for Biomedical Engineering)
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