Special Issue "Soft Corals (Octocorallia) Are Marine Bio-Resources towards Biotechnology and Medical Applications"

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 2096

Special Issue Editors

School of Zoology, George S. Wise Faculty of Life Science, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel
Interests: soft coral taxonomy and biology; symbiotic algae; marine invertebrates; biomaterials; marine natural products and environmentally-friendly antifouling paints
Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel
Interests: marine bio-resources; stem cells differentiation; cells niche; scaffold biomaterials
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Special Issue Information

Dear Colleagues,

Soft corals (=octocorals) have been demonstrated to be a tremendous bioresource with potential for developing biotechnology toward novel medical and pharmaceutical applications. The increasing discoveries of biomaterials alongside biomolecules originating from marine organisms, and in particular from octocorals, have revealed the need for further thorough studies along these lines. The properties and function of marine natural products obtained from octocorals and their symbiotic microorganisms motivate extensive exploration across the oceans. The obtained results exhibit outstanding properties, such as biocompatibility for scaffolding purposes, also being applicable for tissue regeneration and treatment of various diseases. Such discoveries have motivated both the academia and the pharma sectors to further explore possible useful applications. The most significant applications of biomaterials derived from soft corals include medical devices such as for tissue scaffolds, bone implants, antimicrobial and anti-inflammatory agents, drug delivery agents, as well as cosmetic and other medical implementations. The upcoming issue will present novel findings and breakthrough perspectives in the field of octocoral biomaterials and biomolecules while demonstrating promising interdisciplinary approaches across basic and applied research.

Prof. Dr. Yehuda Benayahu
Prof. Dr. Dafna Benayahu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • octocoral bioprospecting
  • drug discovery
  • biomaterials
  • natural products
  • medical devices
  • scaffold and regenerative biology
  • therapeutic applications

Published Papers (1 paper)

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Review

Review
Towards Sustainable Medicinal Resources through Marine Soft Coral Aquaculture: Insights into the Chemical Diversity and the Biological Potential
Mar. Drugs 2022, 20(10), 640; https://doi.org/10.3390/md20100640 - 14 Oct 2022
Cited by 6 | Viewed by 1718
Abstract
In recent decades, aquaculture techniques for soft corals have made remarkable progress in terms of conditions and productivity. Researchers have been able to obtain larger quantities of soft corals, thus larger quantities of biologically active metabolites, allowing them to study their biological activity [...] Read more.
In recent decades, aquaculture techniques for soft corals have made remarkable progress in terms of conditions and productivity. Researchers have been able to obtain larger quantities of soft corals, thus larger quantities of biologically active metabolites, allowing them to study their biological activity in many pharmacological assays and even produce sufficient quantities for clinical trials. In this review, we summarize 201 secondary metabolites that have been identified from cultured soft corals in the era from 2002 to September 2022. Various types of diterpenes (eunicellins, cembranes, spatanes, norcembranes, briaranes, and aquarianes), as well as biscembranes, sterols, and quinones were discovered and subjected to bioactivity investigations in 53 different studies. We also introduce a more in-depth discussion of the potential biological effects (anti-cancer, anti-inflammatory, and anti-microbial) and the mechanisms of action of the identified secondary metabolites. We hope this review will shed light on the untapped potential applications of aquaculture to produce valuable secondary metabolites to tackle current and emerging health conditions. Full article
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