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Special Issue "Nanofibers and Nanoparticles from Marine Biomaterials for Tissue Engineering, Drug Delivery and Other Biomedical Applications"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (20 December 2022) | Viewed by 6771

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Prof. Dr. Vassilios Roussis

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Department of Pharmacy, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Interests: biomedical applications; electrospinning; nanofibers; hybrid materials; marine biopolymers
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Dr. Efstathia Ioannou

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Department of Pharmacy, National and Kapodistrian University of Athens, 157 72 Athens, Greece
Interests: isolation; structure elucidation; marine natural products; marine biopolymers; marine-derived microorganisms
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Dr. Stefanos Kikionis

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Department of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
Interests: bone tissue engineering; pest management; biological materials; medical materials; nanofibers

Special Issue Information

Dear Colleagues,

Nanotechnology represents an emerging technological field in medicine and biomedical engineering. Nanostructured particulate and fibrous systems are attracting constantly increasing attention for the development of novel biomedical systems in tissue-engineering and drug-delivery applications. Various natural and synthetic polymers can be engineered in functionalized and modified hybrid nanostructures with the desired and necessary properties for targeted bioapplications.

Marine biopolymers are considered abundant, cost-efficient, and non-toxic materials, representing a rapidly growing sector of materials in the biomedical field, due to their high biocompatibility and biodegradability, and inherent biological properties.

This Special Issue aims to include original research articles and reviews on the design, development, and detailed characterization of marine-based nanostructured biomaterials with the potential for utilization in various biomedical applications as drug-release modifiers, bioadhesives, cell scaffolds, coatings, wound-dressing materials and tissue-engineering scaffolds.

Prof. Dr. Vassilios Roussis
Prof. Dr. Efstathia Ioannou
Dr. Stefanos Kikionis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

marine biomaterials
marine biopolymers
marine polysaccharides
nanoparticles
nanofibers
biomedical applications
drug delivery
tissue engineering
cell scaffolds

Published Papers (3 papers)

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Research

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Open AccessArticle

Valorization of Fish Waste: Isolation and Characterization of Acid- and Pepsin-Soluble Collagen from the Scales of Mediterranean Fish and Fabrication of Collagen-Based Nanofibrous Scaffolds

Leto-Aikaterini Tziveleka

and

Mar. Drugs 2022, 20(11), 664; https://doi.org/10.3390/md20110664 - 25 Oct 2022

Cited by 2 | Viewed by 1264

Abstract

In search of alternative and sustainable sources of collagenous materials for biomedical applications, the scales of five Mediterranean fish species—fished in high tonnage in the Mediterranean region since they represent popular choices for the local diet—as well as those of the Atlantic salmon for comparison purposes, were comparatively studied for their acid- and pepsin-soluble collagen content. Fish scales that currently represent a discarded biomass of no value could be efficiently exploited for the production of a high added-value biomaterial. The isolated collagenous materials, which showed the typical electrophoretic patterns of type I collagen, were morphologically and physicochemically characterized. Using scanning electron microscopy the fibrous morphology of the isolated collagens was confirmed, while the hydroxyproline content, in conjunction with infrared spectroscopy and X-ray diffraction studies verified the characteristic for collagen amino acid profile and its secondary structure. The acid- and pepsin-soluble collagens isolated from the fish scales were blended with the bioactive sulfated marine polysaccharide ulvan and polyethylene oxide and electrospun to afford nanofibrous scaffolds that could find applications in the biomedical sector. Full article

(This article belongs to the Special Issue Nanofibers and Nanoparticles from Marine Biomaterials for Tissue Engineering, Drug Delivery and Other Biomedical Applications)

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Open AccessArticle

Polymer-Based Electrophoretic Deposition of Nonwovens for Medical Applications: The Effect of Carrier Structure, Solution, and Process Parameters

Ewelina Pabjanczyk-Wlazlo

and

Mar. Drugs 2021, 19(10), 533; https://doi.org/10.3390/md19100533 - 23 Sep 2021

Cited by 6 | Viewed by 1517

Abstract

Hyaluronate and alginate are non-toxic and biocompatible polymers, which can be used for surface modification and functionalization of many kinds of materials. Electrophoretic deposition (EPD) has several advantages, including its versatility, simplicity, and ability to coat substrates with complex shapes, and is used for the creation of antimicrobial or hydrophobic coatings on metallic biomaterials, among other applications. However, its utilization for applying biopolymer layers on textiles is very limited due to the more complex structure and spatial characteristics of fibrous materials. The aim of this research was to analyze the effects of selected EPD process parameters and the structural characteristics of fibrous carriers on the kinetics of the process and the microscopic characteristics of the deposited layers. The influence of solution characteristics, process parameters, and carrier structures obtained using two different techniques (melt blown and spun-bonded) were analyzed. The morphology and structure of the created deposits were analyzed using scanning electron microscopy and computed tomography, and molecular structure analysis was performed with Fourier Transform Infrared spectroscopy. The surface mass and thickness of fibrous poly (lactic acid)-based carriers were analyzed in accordance with the respective standards. This study serves as a basis for discussion and further development of this method with regard to fibrous materials for medical applications. Full article

(This article belongs to the Special Issue Nanofibers and Nanoparticles from Marine Biomaterials for Tissue Engineering, Drug Delivery and Other Biomedical Applications)

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Review

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Open AccessReview

Marine Biopolymers as Bioactive Functional Ingredients of Electrospun Nanofibrous Scaffolds for Biomedical Applications

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Mar. Drugs 2022, 20(5), 314; https://doi.org/10.3390/md20050314 - 05 May 2022

Cited by 13 | Viewed by 2739

Abstract

Marine biopolymers, abundantly present in seaweeds and marine animals, feature diverse structures and functionalities, and possess a wide range of beneficial biological activities. Characterized by high biocompatibility and biodegradability, as well as unique physicochemical properties, marine biopolymers are attracting a constantly increasing interest for the development of advanced systems for applications in the biomedical field. The development of electrospinning offers an innovative technological platform for the production of nonwoven nanofibrous scaffolds with increased surface area, high encapsulation efficacy, intrinsic interconnectivity, and structural analogy to the natural extracellular matrix. Marine biopolymer-based electrospun nanofibrous scaffolds with multifunctional characteristics and tunable mechanical properties now attract significant attention for biomedical applications, such as tissue engineering, drug delivery, and wound healing. The present review, covering the literature up to the end of 2021, highlights the advancements in the development of marine biopolymer-based electrospun nanofibers for their utilization as cell proliferation scaffolds, bioadhesives, release modifiers, and wound dressings. Full article

(This article belongs to the Special Issue Nanofibers and Nanoparticles from Marine Biomaterials for Tissue Engineering, Drug Delivery and Other Biomedical Applications)

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Special Issue "Nanofibers and Nanoparticles from Marine Biomaterials for Tissue Engineering, Drug Delivery and Other Biomedical Applications"

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