Submit to Marine Drugs Review for Marine Drugs Propose a Special Issue

Journal Menu

Journal Browser

► Journal Browser

Special Issue "Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022"

Print Special Issue Flyer
Special Issue Editors
Special Issue Information
Keywords
Related Special Issue
Published Papers

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 7079

Share This Special Issue

Special Issue Editors

Dr. Marcelo D. Catarino

E-Mail Website
Guest Editor

LAQV-REQUIMTE, Department of Chemistry, Universidade de Aveiro, 3810-193 Aveiro, Portugal
Interests: marine resources; seaweeds; natural compounds; polyphenols; structural analysis; bioactive properties; bioacessability; bioavailability and metabolism; (bio)technological applications
Special Issues, Collections and Topics in MDPI journals

Dr. Susana M. Cardoso

E-Mail Website
Guest Editor

LAQV-REQUIMTE, Department of Chemistry, Universidade de Aveiro, 3810-193 Aveiro, Portugal
Interests: natural products; structural analysis; nutrients and bioactive compounds; liquid chromatography; mass spectrometry; antioxidant; bioactivity; bioaccessibility and bioavailability; added-value products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleague,

Due to the extreme conditions and complex habitats they live in, marine organisms have developed unique adaptation mechanisms that have significantly affected the biochemical nature of their primary and/or secondary metabolites. Consequently, marine organisms constitute a great reservoir of numerous bioactive compounds with great industrial and economical interest that do not exist anywhere else. Marine phenolics are a good example of such compounds. Somoe of these molecules present specific structural and biochemical features that cannot be found in land phenolics, granting them particular bioactive properties . In this context, this Special Issue aims to cover the recent breakthroughs on different aspects in the field of marine phenolics including, but not limited, to advances on extraction, purification and characterization techniques, chemistry and structural elucidation, biological properties and the mechanisms behind them, and technological innovations and development of novel value-added products. As Guest Editors, we would like to invite all interested authors to share their work on this topic and submit their contributions, either as original research or review articles, to the current issue of Marine Drugs entitled "Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022".

Dr. Marcelo D. Catarino
Dr. Susana M. Cardoso
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

marine phenolics
extraction
purification
characterization
bioactive properties
technological applications
natural products
functional foods
nutraceuticals
cosmetic
pharmaceutical agents

Related Special Issue

Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications in Marine Drugs (8 articles)

Published Papers (3 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

Jump to: Review

Open AccessArticle

Sargachromenol Isolated from Sargassum horneri Attenuates Glutamate-Induced Neuronal Cell Death and Oxidative Stress through Inhibition of MAPK/NF-κB and Activation of Nrf2/HO-1 Signaling Pathway

and

Mar. Drugs 2022, 20(11), 710; https://doi.org/10.3390/md20110710 - 12 Nov 2022

Cited by 1 | Viewed by 1189

Abstract

Oxidative stress-induced neuronal cell loss is considered to be the major mechanism underlying the pathogenesis of neurodegenerative diseases, which could be induced by a high concentration of glutamate. In this study, sargachromenol (SC) was isolated from a marine brown seaweed Sargassum horneri (S. horneri) and its neuroprotective effects against glutamate-induced oxidative stress in HT22 cells were investigated. An MTT assay was applied to assess the cytotoxicity of the SC, and the efficacies of SC were determined by flow cytometry, an analysis of ROS production, quantitative Real-Time PCR, and the Western blot assay. Our results showed that the pretreatment of SC reduced glutamate-induced apoptosis in HT22 cells via inhibiting the sub-G₁ population, DNA fragmentation, and nuclear condensation, as well as up-regulating anti-apoptotic protein (Bcl-2) and down-regulating apoptotic proteins (Bax, p53, cleaved-PARP, caspase-3, caspase-9, and cytochrome c). Additionally, SC attenuated glutamate-induced oxidative stress by suppressing mitogen-activated protein kinases (MAPKs;ERK, JNK, and p38) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling (IκBα and NF-κB p65), while activating nuclear factor erythroid-2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1) signaling (Nrf2; HO-1, and NQO-1). Our results suggest that SC could be used as a pharmacological candidate for the prevention and treatment of neurodegenerative diseases. Full article

(This article belongs to the Special Issue Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022)

► Show Figures

Figure 1

Open AccessArticle

Effect of Extraction Temperature on Pressurized Liquid Extraction of Bioactive Compounds from Fucus vesiculosus

Adane Tilahun Getachew

Susan Løvstad Holdt

Anne Strunge Meyer

and

Charlotte Jacobsen

Mar. Drugs 2022, 20(4), 263; https://doi.org/10.3390/md20040263 - 12 Apr 2022

Cited by 8 | Viewed by 2242

Abstract

This study was aimed at investigating the effect of low polarity water (LPW) on the extraction of bioactive compounds from Fucus vesiculosus and to examine the influence of temperature on the extraction yield, total phenolic content, crude alginate, fucoidan content, and antioxidant activity. The extractions were performed at the temperature range of 120–200 °C with 10 °C increments, and the extraction yield increased linearly with the increasing extraction temperature, with the highest yields at 170–200 °C and with the maximum extraction yield (25.99 ± 2.22%) at 190 °C. The total phenolic content also increased with increasing temperature. The extracts showed a high antioxidant activity, measured with DPPH (2,2-Diphenyl-1-picrylhydrazyl) radicals scavenging and metal-chelating activities of 0.14 mg/mL and 1.39 mg/mL, respectively. The highest yield of alginate and crude fucoidan were found at 140 °C and 160 °C, respectively. The alginate and crude fucoidan contents of the extract were 2.13% and 22.3%, respectively. This study showed that the extraction of bioactive compounds from seaweed could be selectively maximized by controlling the polarity of an environmentally friendly solvent. Full article

(This article belongs to the Special Issue Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022)

► Show Figures

Figure 1

Review

Jump to: Research

Open AccessReview

Overview of Phlorotannins’ Constituents in Fucales

and

Mar. Drugs 2022, 20(12), 754; https://doi.org/10.3390/md20120754 - 30 Nov 2022

Cited by 7 | Viewed by 2953

Abstract

Fucales are an order within the Phaeophyceae that include most of the common littoral seaweeds in temperate and subtropical coastal regions. Many species of this order have long been a part of human culture with applications as food, feedand remedies in folk medicine. Apart from their high nutritional value, these seaweeds are also a well-known reservoir of multiple bioactive compounds with great industrial interest. Among them, phlorotannins, a unique and diverse class of brown algae-exclusive phenolics, have gathered much attention during the last few years due to their numerous potential health benefits. However, due to their complex structural features, combined with the scarcity of standards, it poses a great challenge to the identification and characterization of these compounds, at least with the technology currently available. Nevertheless, much effort has been taken towards the elucidation of the structural features of phlorotannins, which have resulted in relevant insights into the chemistry of these compounds. In this context, this review addresses the major contributions and technological advances in the field of phlorotannins extraction and characterization, with a particular focus on Fucales. Full article

(This article belongs to the Special Issue Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022)

► Show Figures

Journal Menu

Journal Browser

Special Issue "Marine Phenolics: Extraction and Purification, Identification, Characterization and Applications 2022"

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Related Special Issue

Published Papers (3 papers)

Research

Review

Further Information

Guidelines

MDPI Initiatives

Follow MDPI