Special Issue "Marine Bioactive Compound Discovery through OSMAC Approach"
A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".
Deadline for manuscript submissions: 29 February 2024 | Viewed by 1412
Marine microorganisms have proven to be a source of novel natural products with variety biological activities. However, because of the limitations of the traditional natural product mining methods, the number of gene clusters potentially encoding the production of natural products and the actual number of chemically characterized metabolites for a given microorganism are widely different.
In recent years, with the rapid development of gene sequencing technology and bioinformatics, cryptic metabolic pathways can be accessed using molecular techniques or cultivation-based approaches. The OSMAC approach (one strain—many compounds), based on modification of growth conditions, has proven to be a powerful strategy for the discovery of new cryptic natural products. The addition of chemical elicitors or epigenetic modifiers have also been used to activate silent genes.
This Special Issue invites articles from both molecular techniques or cultivation-based approaches on marine microorganisms with a focus on natural product discovery and characterization. We particularly welcome articles that combine genomic, metabolomic, and epigenetic approaches with OSMAC for the characterization of marine microorganism secondary metabolites.
Dr. Xiaoling Lu
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- marine microorganisms
- secondary metabolites