Special Issue "An Update on SARS‐CoV‐2: Mutations, Variants, and Their Potential Impact"
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 11872
Interests: SARS-CoV-2; drug resistance; vaccine escape; HBV chronic infection; HBV reactivation; hepatocellular carcinoma; HIV
Interests: SARS-CoV-2; drug resistance; immune escape; HBV chronic infection; HBV reactivation; hepatocellular carcinoma; HIV; HDV
Special Issues, Collections and Topics in MDPI journals
Special Issue in Vaccines: New Challenges for Natural and Vaccine-Induced Immunity against HBV Infection
Special Issue in Pathogens: Viral Hepatitis in Europe: The Unresolved Issues
Special Issue in Viruses: Virological and Immunological Factors Underlying HBV Functional Cure and HBV Reactivation
Since the beginning of the 21st century, coronaviruses have been considered highly pathogenic and transmissible emerging viruses causing SARS, MERS, and COVID-19. SARS-CoV-2, the etiological agent of COVID-19, is currently undergoing a process of genetic diversification during its spread across humans. An increasing body of evidence highlights that emerging SARS-CoV-2 mutations and variants could play crucial roles in promoting viral evasion from immune responses, including those elicited by vaccination, in hampering the effectiveness of the current diagnostic assays, and in favoring reinfection events. Knowledge about viral mutations and genetic variations can help to better understand viral pathogenicity, immunity, and design of accurate diagnostic assays.
This Special Issue is aimed at providing a comprehensive overview of the key areas of genetic diversification, adaptation, and evolution underlying SARS-CoV-2 infection. Original research, review, clinical reports that afford up-to-date findings in the topics of SARS-CoV-2 viral genetic variation, intergenic co-evolution, geographical adaptation, immune and diagnostic evasion, natural drug resistance, mutational impact on SARS-CoV-2 structural protein stability, and genetic compartmentalization in body districts are of great interest and will be welcome.
Dr. Romina Salpini
Prof. Dr. Valentina Svicher
Dr. Mohammad Alkhatib
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- SARS-CoV-2 mutations and variants
- genetic adaptation
- genetic conservation and diversification
- sequence variations
- phylogenetic analysis
- mutation impact
- immune evasion
- drug resistance
- 3D structural analysis