Application of Endoscopic Imaging in Gastrointestinal Disease

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Radiobiology and Nuclear Medicine".

Deadline for manuscript submissions: closed (24 February 2023) | Viewed by 3923

Special Issue Editors


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Guest Editor
Department of Gastroenterology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
Interests: endoscopy; endoscopic ultrasound; gastrointestinal diseases; gastrointestinal malignancies; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, 200638 Craiova, Romania
Interests: HCV

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Guest Editor
Digestive Endoscopy Unit, University Clinic "Dr Dragisa Misovic-Dedinje", Belgrade 11000, Serbia
Interests: chronic pancreatitis; exocrine pancreatic insufficiency; pancreatic cancer; pancreatic tuberculosis

Special Issue Information

Dear Colleagues,

Since the introduction of flexible endoscopy more than 50 years ago, endoscopic imaging has kept pace with technological developments, and additional techniques have been introduced to help clinicians in the decision-making process. At present, endoscopic imaging techniques are routinely considered for both the diagnosis and therapeutic management of gastrointestinal disease, and many guidelines have been developed to provide a more standardized approach.

Novel endoscopic imaging techniques such as narrow-spectrum endoscopy or even confocal laser endomicroscopy have been continuously introduced to improve the early diagnosis of gastrointestinal disease. Both early diagnosis and the ability to distinguish between benign and malignant lesions have enhanced the endoscopy technology spectrum, and are currently facing new challenges such as oncologic targeted therapy. Providing information about mucosa characteristics, as well as the capability of providing both local or advanced therapeutic endoscopic methods, have resulted in path-breaking development of gastrointestinal disease management. At the core of the endoscopic imaging revolution lies the need for new methods for the diagnosis and therapy of gastrointestinal disease. 

Nonetheless, the use of ERCP and endoscopic ultrasound (EUS) has also opened new avenues by providing access to the biliary tract. Particularly, EUS offers access to the nearby organs of the gastrointestinal tract and may also be used as a valid tool for local tumor staging. Currently, the use of artificial intelligence for endoscopic imaging is standing as a new tool that may aid physicians in their clinical practice.

In this Special Issue, we focus on the use of endoscopic imaging for gastrointestinal disease. From white light endoscopy to “red flag techniques” and confocal laser endomicroscopy as well as ERCP and EUS, we would like to invite researchers to share their experiences by submitting their high-quality papers.

Dr. Bogdan Silviu Ungureanu
Prof. Dr. Ion Rogoveanu
Dr. Nikola Panić
Guest Editors

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Keywords

  • endoscopy
  • colonoscopy
  • narrow-spectrum endoscopy
  • confocal laser endomicroscopy
  • video capsule endoscopy
  • ERCP
  • endoscopic ultrasound (EUS)
  • gastrointestinal disease
  • artificial intelligence

Published Papers (2 papers)

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18 pages, 8573 KiB  
Article
Semantic Segmentation of Digestive Abnormalities from WCE Images by Using AttResU-Net Architecture
by Samira Lafraxo, Meryem Souaidi, Mohamed El Ansari and Lahcen Koutti
Life 2023, 13(3), 719; https://doi.org/10.3390/life13030719 - 07 Mar 2023
Cited by 12 | Viewed by 2248
Abstract
Colorectal cancer is one of the most common malignancies and the leading cause of cancer death worldwide. Wireless capsule endoscopy is currently the most frequent method for detecting precancerous digestive diseases. Thus, precise and early polyps segmentation has significant clinical value in reducing [...] Read more.
Colorectal cancer is one of the most common malignancies and the leading cause of cancer death worldwide. Wireless capsule endoscopy is currently the most frequent method for detecting precancerous digestive diseases. Thus, precise and early polyps segmentation has significant clinical value in reducing the probability of cancer development. However, the manual examination is a time-consuming and tedious task for doctors. Therefore, scientists have proposed many computational techniques to automatically segment the anomalies from endoscopic images. In this paper, we present an end-to-end 2D attention residual U-Net architecture (AttResU-Net), which concurrently integrates the attention mechanism and residual units into U-Net for further polyp and bleeding segmentation performance enhancement. To reduce outside areas in an input image while emphasizing salient features, AttResU-Net inserts a sequence of attention units among related downsampling and upsampling steps. On the other hand, the residual block propagates information across layers, allowing for the construction of a deeper neural network capable of solving the vanishing gradient issue in each encoder. This improves the channel interdependencies while lowering the computational cost. Multiple publicly available datasets were employed in this work, to evaluate and verify the proposed method. Our highest-performing model was AttResU-Net, on the MICCAI 2017 WCE dataset, which achieved an accuracy of 99.16%, a Dice coefficient of 94.91%, and a Jaccard index of 90.32%. The experiment findings show that the proposed AttResU-Net overcomes its baselines and provides performance comparable to existing polyp segmentation approaches. Full article
(This article belongs to the Special Issue Application of Endoscopic Imaging in Gastrointestinal Disease)
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12 pages, 28771 KiB  
Case Report
Duodenal Gangliocytic Paragangliomas—Case Series and Literature Review
by Madalina Stan-Ilie, Vasile Şandru, Oana-Mihaela Plotogea, Ecaterina Rînja, Christopher Pavel, Gabriel Constantinescu, Lucian Negreanu, Dan Nicolae Paduraru, Alexandra Bolocan, Octavian Andronic, Dragos Davitoiu, Gheorghe G. Bălan and Alexandru Constantinescu
Life 2023, 13(3), 597; https://doi.org/10.3390/life13030597 - 21 Feb 2023
Cited by 1 | Viewed by 1229
Abstract
Duodenal gangliocytic paragangliomas are rare neuroendocrine tumors primarily localized in the periampullary area. Though mostly asymptomatic, they can present with various symptoms, most often jaundice, anemia and abdominal pain. The present paper is a case series report, describing our personal experience with patients [...] Read more.
Duodenal gangliocytic paragangliomas are rare neuroendocrine tumors primarily localized in the periampullary area. Though mostly asymptomatic, they can present with various symptoms, most often jaundice, anemia and abdominal pain. The present paper is a case series report, describing our personal experience with patients presenting to the Emergency Unit with different symptoms due to duodenal gangliocytic paraganglioma. Endoscopic resection is safe and indicated in most of the cases, being also associated with lower medical costs. EUS plays a central role in the pre-resection management and in surveillance, and immunostaining is decisive to ascertain the tumor histologic origin. In addition to reporting our experience, we researched the literature regarding these rare tumors and performed a comprehensive review. Full article
(This article belongs to the Special Issue Application of Endoscopic Imaging in Gastrointestinal Disease)
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