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Life
Special Issues
Imaging in Neurosurgery: State of the Art
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Imaging in Neurosurgery: State of the Art

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (10 September 2022) | Viewed by 2945

Special Issue Editors

Dr. Federico Bruno

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Guest Editor
Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, Italy
Interests: neuroradiology; MRI; focused ultrasound; tremor; spine imaging
Dr. Ayesha Jameel

E-Mail Website
Guest Editor
Division of Brain Sciences, Imperial College London, London SW7 2BX, UK
Interests: neuroradiology; neurodegenerative and movement disorders; focused ultrasound (FUS); essential tremor; Parkinson’s disease
Dr. Yanmei Tie

E-Mail Website
Guest Editor
Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Interests: functional MRI; surgical planning; functional brain mapping; brain connectivity; diffusion MRI; brain tumor

Special Issue Information

Dear Colleagues,

Neuroimaging plays a fundamental and essential role in the neurosurgical treatment of most brain and spine pathologies. The preoperative study of brain tumors is certainly a milestone in the application of presurgical neuroimaging; structural and functional imaging using advanced MRI sequences (such as perfusion imaging, functional MRI (fMRI), and diffusion MRI (dMRI) sequences) provide fundamental information for the selection of surgical candidates, the tailoring of individualized surgical planning based on structural and functional organization of the brain, and the prediction of postoperative functional outcome. Emerging radiomics techniques will also be implemented in the near future to increase the diagnostic and prognostic validity of neuroimaging data.

Accurate anatomical targeting through neuroimaging techniques is also crucial for optimal clinical outcomes in functional neurosurgical ablation and stimulation procedures such as DBS.

Imaging guidance indeed represents the basis of numerous growing minimally invasive neurosurgical treatments, such as the MRgFUS, used predominantly for the treatment of tremor and chronic pain, but with interesting perspectives in the treatment of epilepsy, psychiatric disorders, drug delivery and brain tumors.

Neuroimaging also plays a central and ever-expanding role in image-guided neurosurgery, thanks to the technological development of scanners and the advent of fusion imaging (MR-CT, MR-US), with a broad range of applications in brain and spine surgery.

This Special Issue aims to present the latest advances in the cross-disciplinary field of neuroimaging in neurosurgery, to build a focused update from different points of view. We welcome contributions from all specialists involved in the diagnosis and treatment of neurosurgical diseases, from basic neurological sciences (neuroanatomy, neurobiology) to medical clinical specialties (neurology, neurosurgery, neuroradiology, neurophysiology).

Dr. Federico Bruno
Dr. Ayesha Jameel
Dr. Yanmei Tie
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurosurgery
  • neuroimaging
  • MRI
  • radiomics
  • brain tumors
  • functional neurosurgery
  • surgical planning
  • functional brain mapping
  • image-guided neurosurgery

Published Papers (1 paper)

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Research

13 pages, 6581 KiB  
Article
Diffusion Tensor Imaging of a Median Nerve by Magnetic Resonance: A Pilot Study
by Kanza Awais, Žiga Snoj, Erika Cvetko and Igor Serša
Life 2022, 12(5), 748; https://doi.org/10.3390/life12050748 - 18 May 2022
Cited by 2 | Viewed by 1853
Abstract
The magnetic resonance Diffusion Tensor Imaging (DTI) is a powerful extension of Diffusion Weighted Imaging (DWI) utilizing multiple bipolar gradients, allowing for the evaluation of the microstructural environment of the highly anisotropic tissues. DTI was predominantly used for the assessment of the central [...] Read more.
The magnetic resonance Diffusion Tensor Imaging (DTI) is a powerful extension of Diffusion Weighted Imaging (DWI) utilizing multiple bipolar gradients, allowing for the evaluation of the microstructural environment of the highly anisotropic tissues. DTI was predominantly used for the assessment of the central nervous system (CNS), but with the advancement in magnetic resonance (MR) hardware and software, it has now become possible to image the peripheral nerves which were difficult to evaluate previously because of their small caliber. This study focuses on the assessment of the human median peripheral nerve ex vivo by DTI microscopy at 9.4 T magnetic field which allowed the evaluation of diffusion eigenvalues, the mean diffusivity and the fractional anisotropy at 35 μm in-plane resolution. The resolution was sufficient for clear depiction of all nerve anatomical structures and therefore further image analysis allowed the obtaining of average values for DT parameters in nerve fascicles (intrafascicular region and perineurium) as well as in the surrounding epineurium. The results confirmed the highest fractional anisotropy of 0.33 and principal diffusion eigenvalue of 1.0 × 10−9 m2/s in the intrafascicular region, somewhat lower values of 0.27 and 0.95 × 10−9 m2/s in the perineurium region and close to isotropic with very slow diffusion (0.15 and 0.05 × 10−9 m2/s) in the epineurium region. Full article
(This article belongs to the Special Issue Imaging in Neurosurgery: State of the Art)
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