Molecular Mechanisms of Preeclampsia

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 51

Special Issue Editor

E-Mail Website
Guest Editor
Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7525, USA
Interests: roles of maternal genetic factors in preeclampsia and trophoblast biology; the beneficial effects of small molecules (e.g., nicotinamide) on preeclampsia and associated mechanisms

Special Issue Information

Dear Colleagues,

Preeclampsia is a pregnancy-related disorder, characterized by maternal hypertension, proteinuria and end-organ damage. It affects approximately 5–8% of all pregnancies and is a leading cause of both maternal and neonatal morbidity and mortality. The mothers and children of preeclamptic pregnancies are at increased risk for cardiovascular diseases and cognitive disorders later in life. Currently, there is no effective way to predict and treat preeclampsia; the ultimate treatment is delivery of the baby and placenta as physicians did a century ago.

Various molecules and pathways are involved in preeclampsia pathogenesis. The aim of this Special Issue is to provide an overview of the molecules and pathways involved in preeclampsia in order to better understand the molecular mechanisms of this disorder and identify potential targets for intervention. We are welcoming submissions of original research articles and reviews on topics relevant to any aspect of preeclampsia pathogenesis.

Dr. Feng Li
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • preeclampsia
  • hypertension
  • proteinuria
  • placenta
  • fetal growth restriction
  • pregnancy com-plications
  • implantation

Published Papers

This special issue is now open for submission.
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