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Life
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HIV and STIs Prevention
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HIV and STIs Prevention

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2129

Special Issue Editors

Dr. Agnese Colpani

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Guest Editor
Department of Medicine, Surgery, and Pharmacy, University of Sassari, 07100 Sassari, Italy
Interests: HIV infection; sexually transmitted infection; prevention; SARS-CoV-2 infection; viral infection; parasitology
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea De Vito

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Guest Editor
Department of Medicine, Surgery, and Pharmacy, University of Sassari, 07100 Sassari, Italy
Interests: HIV; antiviral treatment; HIV resistances; zoonotic diseases; SARS-CoV-2; COVID-19; bacterial infections
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

HIV (human immunodeficiency virus) is a virus that attacks cells that help the body fight infection, making a person more vulnerable to other infections and diseases. It is spread by contact with certain bodily fluids of a person with HIV, most commonly during unprotected sex, or through sharing injection drug equipment. If left untreated, HIV can lead to AIDS (acquired immunodeficiency syndrome).

In 2020, about 37 million people worldwide were living with HIV and 680,000 deaths occurred in that year. HIV/AIDS has had a large impact on society, both as an illness and as a source of discrimination. The number of new yearly cases is decreasing but still represents an international concern. On the contrary, the number of Sexually transmitted infections (STIs) is increasing.

This Special Issue of Life is designed to enable the rapid publication and dissemination of innovative research with the aim of advancing scientific knowledge and highlighting future perspectives about the prevention of HIV and STIs. Research articles, reviews (narrative or systematic) and metanalysis will be considered for publications.

Dr. Agnese Colpani
Dr. Andrea De Vito
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HIV
  • PREP
  • PEP
  • DoxyPREP
  • treatment as prevention
  • U=U
  • STIs
  • awareness campaign
  • vulnerable populations
  • screening

Published Papers (2 papers)

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Research

7 pages, 224 KiB  
Communication
The Impact of Number of Medications on Falls in Aging Persons with Human Immunodeficiency Virus
by Leanne W. Thai, Lucas Hill, Shannon Balcombe, Afsana Karim and Maile Young Karris
Life 2023, 13(9), 1848; https://doi.org/10.3390/life13091848 - 31 Aug 2023
Cited by 1 | Viewed by 604
Abstract
We aimed to evaluate the impact of polypharmacy on the risk of having a fall in older persons with HIV (PWH). PWH at least 50 years of age who were seen at our institution from September 2012 to August 2017 were included. Unique [...] Read more.
We aimed to evaluate the impact of polypharmacy on the risk of having a fall in older persons with HIV (PWH). PWH at least 50 years of age who were seen at our institution from September 2012 to August 2017 were included. Unique participants were selected for either a case or control cohort depending on the presence of a documented fall during the study time period. Demographics, HIV-related measures, VACS score, number of medications, as well as the impact of taking benzodiazepines and opioids were compared between the two cohorts. Fall was documented for 637 patients compared to 1534 without a fall during the same time period. Multivariable logistic regression revealed that the total number of medications, having a higher VACS score, taking an opioid, being female sex assigned at birth, and having a lower nadir CD4 count were significantly associated with higher odds of having a fall. In this cohort of older PWH, taking a higher number of non-ARV medications significantly increased the odds of having a fall. In addition, taking an opioid resulted in the highest odds of having a fall. These results suggest the importance of deprescribing and addressing opioid use in reducing the risk of having a fall in older PWH. Full article
(This article belongs to the Special Issue HIV and STIs Prevention)
12 pages, 256 KiB  
Article
HIV-Indicator Condition Guided Testing in a Hospital Setting
by Diletta Barbanotti, Camilla Tincati, Alessandro Tavelli, Andrea Santoro, Matteo Sala, Teresa Bini, Anna De Bona, Antonella d’Arminio Monforte and Giulia Carla Marchetti
Life 2023, 13(4), 1014; https://doi.org/10.3390/life13041014 - 14 Apr 2023
Cited by 3 | Viewed by 988
Abstract
Late diagnosis is still a major issue in HIV infection management, leading to important consequences for both patients and community. In this perspective, HIV screening targeted on some clinical conditions (HIV indicator conditions—HIVICs) emerged as a useful strategy, also involving patients not considered [...] Read more.
Late diagnosis is still a major issue in HIV infection management, leading to important consequences for both patients and community. In this perspective, HIV screening targeted on some clinical conditions (HIV indicator conditions—HIVICs) emerged as a useful strategy, also involving patients not considered at high behavioral risk. We organized an in-hospital HIVICs guided screening campaign named ICEBERG in Milan, Italy, between 2019 and 2021. Among the 520 subjects enrolled, mainly presenting with viral hepatitis or mononucleosis-like syndrome, 20 resulted HIV positive (3.8% prevalence). A significant proportion of them had multiple conditions and advanced immunosuppression, with 40% being AIDS-presenters. As adherence to the screening campaign was modest for non-ID specialists, educational interventions to raise clinicians’ sensitivity are urgently needed. HIV-ICs guided testing was confirmed as a useful tool, but a combined approach with other screening strategies seems to be essential for early HIV diagnosis. Full article
(This article belongs to the Special Issue HIV and STIs Prevention)
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