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Life
Special Issues
Oral Microbiology Associated with Oral Diseases or Lesions
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Special Issue "Oral Microbiology Associated with Oral Diseases or Lesions"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: closed (7 July 2023) | Viewed by 2120

Special Issue Editors

Dr. Gustavo Fernandes

E-Mail Website
Guest Editor
Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA
Interests: bone grafting and biology; tissue repair; material testing; gingival recession; image analysis (histomorphometry and stereology); stem cell research; laser treatment; blood concentrates; dental implants; oral rehabilitation
Special Issues, Collections and Topics in MDPI journals
Dr. Wenwen Liu

E-Mail Website
Guest Editor
School and Hospital of Stomatologhy, Peking University, Beijing, China
Interests: magnetoelectric chiral biomaterials; bone regeneration; osteoimmunology

Special Issue Information

Dear Colleagues,

Oral Microbiology is characterized by complexity. Biofilms on oral surfaces contain tens or hundreds of different species, all interacting and contributing to the system's overall function. Also, the biofilm interacts with host tissues and with environmental factors such as dietary intake or inhalation of smoke.
Oral biofilms are present in health and diseases, which can be caused by dysbiosis. Nevertheless, some combinations of microorganisms are more prone to developing the disease than others. Therefore, understanding the transition from health to disease is critical for rationalizing new strategies to enhance oral health.
Thus, more studies are needed before we can fully understand how and why oral disease occurs.

  • Correlation of the microbiota and diseases
  • Dysbiosis
  • Unbalance system (oral and systemic diseases)
  • Technological devices associated with microbiology
  • Homeostasis and Allostasis
  • Gengivitis, Periodontitis, Peri-implant mucositis, and Peri-implantitis

Dr. Gustavo Fernandes
Dr. Wenwen Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • periodontics
  • diseases
  • oral lesions
  • microbiology

Published Papers (2 papers)

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Research

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Article
Evaluation of the Cariogenic and Anti-Cariogenic Potential of Human Colostrum and Colostrum-Derived Probiotics: Impact on S. mutans Growth, Biofilm Formation, and L. rhamnosus Growth
by
Samaa A. Zaghloul
,
Sara N. Hashem
,
Safaa R. El-Sayed
,
Mona Shaban E. M. Badawy
,
Sarah I. Bukhari
,
Heba Mohammed Refat M. Selim
and
Omnia Karem M. Riad
Life 2023, 13(9), 1869; https://doi.org/10.3390/life13091869 - 05 Sep 2023
Viewed by 308
Abstract
Human colostrum (HC) is essential for oral health as it is rich in probiotics that could affect the growth of the cariogenic S. mutans and its biofilm formation; hindering dental caries in advance. In this study, HC was collected from 36 healthy mothers [...] Read more.
Human colostrum (HC) is essential for oral health as it is rich in probiotics that could affect the growth of the cariogenic S. mutans and its biofilm formation; hindering dental caries in advance. In this study, HC was collected from 36 healthy mothers 1–3 days postpartum. The effect of HC on oral health was carried out by assessing the impact of HC and its derived probiotics’ cell-free supernatants (CFS) on the growth of S. mutans (using modified well diffusion) and its biofilm formation (using microtiter plate assay). Moreover, the effect of whole HC on L. rhamnosus, a probiotic oral bacterium, was examined. Probiotics were isolated and identified phenotypically by API 50 CH carbohydrate fermentation and genotypically by 16S rRNA amplification. The in vitro study revealed that HC has cariogenic activity and is associated with biofilm formation. Biofilm strength was inversely proportional to HC dilution (p-value < 0.0001). Nevertheless, HC and colostrum-derived probiotics improve oral health by inhibiting the growth of caries-inducing S. mutans with lower inhibition to L. rhamnosus probiotics. The CFS of isolated probiotics reduced the biofilm formation via the cariogenic S. mutans. These results are not only promising for caries eradication, but they also highlight the importance of breastfeeding infants from their first hours to shape healthy oral microbiota, protecting them from various diseases including dental caries. Full article
(This article belongs to the Special Issue Oral Microbiology Associated with Oral Diseases or Lesions)
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Review

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Review
Current Infections of the Orofacial Region: Treatment, Diagnosis, and Epidemiology
by
Elahe Tahmasebi
,
Ali Keshvad
,
Mostafa Alam
,
Kamyar Abbasi
,
Saeide Rahimi
,
Farzad Nouri
,
Mohsen Yazdanian
,
Hamid Tebyaniyan
,
Artak Heboyan
and
Gustavo Vicentis Oliveira Fernandes
Life 2023, 13(2), 269; https://doi.org/10.3390/life13020269 - 18 Jan 2023
Cited by 7 | Viewed by 1543
Abstract
Undoubtedly, diagnosing and managing infections is one of the most challenging issues for orofacial clinicians. As a result of the diversity of symptoms, complicated behavior, and sometimes confusing nature of these conditions, it has become increasingly difficult to diagnose and treat them. It [...] Read more.
Undoubtedly, diagnosing and managing infections is one of the most challenging issues for orofacial clinicians. As a result of the diversity of symptoms, complicated behavior, and sometimes confusing nature of these conditions, it has become increasingly difficult to diagnose and treat them. It also highlights the need to gain a deeper insight into the orofacial microbiome as we try to improve our understanding of it. In addition to changes in patients’ lifestyles, such as changes in diet, smoking habits, sexual practices, immunosuppressive conditions, and occupational exposures, there have been changes in patients’ lifestyles that complicate the issue. Recent years have seen the development of new infection treatments due to the increased knowledge about the biology and physiology of infections. This review aimed to provide a comprehensive overview of the types of infections in the mouth, including the types that viruses, fungi, or bacteria may cause. It is important to note that we searched the published literature in the Scopus, Medline, Google Scholar, and Cochran databases from 2010 to 2021 using the following keywords: “Orofacial/Oral Infections,” “Viral/Fungal/Bacterial Infections”, “Oral Microbiota” And “Oral Microflora” without limiting our search to languages and study designs. According to the evidence, the most common infections in the clinic include herpes simplex virus, human papillomavirus, Candida albicans, Aspergillus, Actinomycosis, and Streptococcus mutans. The purpose of this study is to review the new findings on characteristics, epidemiology, risk factors, clinical manifestations, diagnosis, and new treatment for these types of infectious diseases. Full article
(This article belongs to the Special Issue Oral Microbiology Associated with Oral Diseases or Lesions)
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