Novel Insights into the Regulation of Plant Specialized Metabolism

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 91

Special Issue Editor

Dr. Yongliang Liu
E-Mail Website
Guest Editor
Kentucky Tobacco Research and Development Center (KTRDC), University of Kentucky, Lexington, KY 40503, USA
Interests: plant specialized metabolism

Special Issue Information

Dear Colleagues,

Plants synthesize over 200,000 chemically diverse specialized metabolites (SMs), which are primarily categorized into three groups: phenolic compounds, terpenoids, and alkaloids. These SMs accumulate in specific plant tissues or during particular developmental stages and play a crucial role in defending plants against various biotic and abiotic stresses. Furthermore, many of these SMs possess inherent therapeutic properties that are beneficial to human health. Therefore, obtaining a deeper understanding of the regulatory mechanisms governing SM biosynthesis presents a significant promise in enhancing crop productivity and the production of valuable chemicals.

SM biosynthesis can be regulated at multiple levels:

  • The transcriptional level: Transcription factors (TFs) directly target and control the expression of genes involved in the SM pathways;
  • The post-transcriptional level: Small RNAs target and modulate the abundance of transcripts encoding SM pathway enzymes;
  • The post-translational level: The activities of TFs and SM pathway enzymes can be altered through various types of modifications, such as phosphorylation.

The objective of this Special Issue is to present a compilation of original research articles and reviews in the field of SM regulation. We enthusiastically invite researchers to submit their work and perspectives to contribute to our collective understanding of this crucial topic.

Dr. Yongliang Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • specialized metabolites
  • regulation
  • transcription factors
  • small RNA
  • phosphorylation

Published Papers

This special issue is now open for submission.
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