Neurotrophic Factors: Their Roles in Disease and Therapeutics
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Pharmaceutical Science".
Deadline for manuscript submissions: closed (2 June 2023) | Viewed by 171
Special Issue Editor
Interests: peripheral nerve injury and regeneration, urological disease, neuroimmunology, electrical stimulation for peripheral nerve regeneration, and potential therapeutics
Special Issue Information
Dear Colleagues,
This Special Issue will focus on neurotrophic factors, an influential group of neuroregenerative molecules, including neurotrophins, glial cell line neurotrophic factors, and neuroprotective cytokines. These factors are essential to the development of the nervous system and regeneration after an injury. They also play an important role in many diseases, both neurological and non-neurological. Brain-derived neurotrophic factor (BDNF), neurturin, and persephin are important to the development of disorders such as depression and Parkinson’s disease. At the same time, it has been demonstrated that nerve growth factor is involved in painful bladder syndrome, and BDNF could be a potential therapeutic for stress urinary incontinence. Additionally, artemin has been shown to promote oncogenicity and drug resistance in cancer cells. This Special Issue will focus on the role of neurotrophic factors in the development, normal function, and disease states of the nervous system, their roles in non-neurological diseases, and potential therapies. Continued understanding of these neurotrophic factors and the ones listed below will improve our understanding of the normal function of the nervous system, as well as disease development and could lead to new therapeutic options.
Dr. Brian Balog
Guest Editor
Manuscript Submission Information
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Keywords
- ciliary neurotrophic factor
- glial derived neurotrophin factor
- leukemia inhibitor factor
- insulin like growth factor 1
- neurotrophin 3
- neurotrophin 4
- pleiotrophin
