Best Practices in Acute Coronary Syndromes

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (26 May 2023) | Viewed by 2961

Special Issue Editors

Cardiology Clinic, ‘Hippokration’ General Hospital, School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece
Interests: clinical and molecular cardiology; endothelial function; arterial stiffness
Special Issues, Collections and Topics in MDPI journals
1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece
Interests: imaging; prevention; inflammation

Special Issue Information

Dear Colleagues,

Acute coronary syndromes remain a major cause of sudden cardiac death and mortality worldwide, despite advancements in diagnostic and therapeutic approaches. Major risk factors for acute coronary syndromes are standard modifiable cardiovascular risk factors (SMURFs), although a proportion of patients present with acute coronary syndromes in the absence of SMURFs. In this Special Issue we provide an overview of SMURFs and non-SMURFs for acute coronary syndromes, optimal pharmacological and invasive treatment, lipid-lowering strategies, anti-diabetic medication and novel anti-inflammatory treatments. We also discuss the diagnostic and prognostic role of plasma and imaging biomarkers in acute coronary syndromes, including the role of coronary CT angiography and perivascular fat imaging.

Prof. Dr. Dimitris Tousoulis
Dr. Alexios S Antonopoulos
Guest Editors

Manuscript Submission Information

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Keywords

  • acute coronary syndromes
  • inflammation
  • satherosclerosis
  • imaging
  • biomarkers

Published Papers (2 papers)

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Review

19 pages, 317 KiB  
Review
Catheter Ablation for the Management of Atrial Fibrillation: An Update of the Literature
by Shahana Hussain, Catrin Sohrabi, Rui Providencia, Syed Ahsan and Nikolaos Papageorgiou
Life 2023, 13(8), 1784; https://doi.org/10.3390/life13081784 - 21 Aug 2023
Cited by 2 | Viewed by 1264
Abstract
Catheter ablation has been shown to be more effective at maintaining sinus rhythm and improving quality of life when compared to antiarrhythmic drugs. Radiofrequency and cryoablation are two effective methods. However, catheter-only ablation strategies have not consistently produced high success rates in treating [...] Read more.
Catheter ablation has been shown to be more effective at maintaining sinus rhythm and improving quality of life when compared to antiarrhythmic drugs. Radiofrequency and cryoablation are two effective methods. However, catheter-only ablation strategies have not consistently produced high success rates in treating longstanding and persistent AF patients. The emerging treatment of choice for such cases is hybrid ablation, which involves a multidisciplinary and minimally invasive approach to achieve surgical ablation of the direct posterior left atrial wall in combination with endocardial catheter ablation. Studies have shown promising results for the hybrid approach when compared with catheter ablation alone, but it is not without risks. Large and randomised studies are necessary to further evaluate these strategies for managing AF. Full article
(This article belongs to the Special Issue Best Practices in Acute Coronary Syndromes)
15 pages, 1310 KiB  
Review
Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease
by Elisabetta Tonet, Alberto Boccadoro, Marco Micillo, Marta Cocco, Alberto Cossu, Graziella Pompei, Melchiore Giganti and Gianluca Campo
Life 2023, 13(5), 1086; https://doi.org/10.3390/life13051086 - 26 Apr 2023
Cited by 1 | Viewed by 1261
Abstract
Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent technologic [...] Read more.
Nowadays, coronary computed tomography angiography (CCTA) has a role of paramount importance in the diagnostic algorithm of ischemic heart disease (IHD), both in stable coronary artery disease (CAD) and acute chest pain. Alongside the quantification of obstructive coronary artery disease, the recent technologic developments in CCTA provide additional relevant information that can be considered as “novel markers” for risk stratification in different settings, including ischemic heart disease, atrial fibrillation, and myocardial inflammation. These markers include: (i) epicardial adipose tissue (EAT), associated with plaque development and the occurrence of arrhythmias; (ii) late iodine enhancement (LIE), which allows the identification of myocardial fibrosis; and (iii) plaque characterization, which provides data about plaque vulnerability. In the precision medicine era, these emerging markers should be integrated into CCTA evaluation to allow for the bespoke interventional and pharmacological management of each patient. Full article
(This article belongs to the Special Issue Best Practices in Acute Coronary Syndromes)
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