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Special Issue "Lyme Disease-An Incompletely Solved Puzzle"
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".
Deadline for manuscript submissions: 14 July 2023 | Viewed by 6010
Special Issue Editor
Interests: lyme carditis; skin and soft tissue infections; surgery; molecular medicine
Special Issue Information
Lyme disease is a multisystem illness caused by spirochete Borrelia burgdorferi (named in honor of the microbiologist Dr. Willy Burgdorfer, who isolated it in 1982) and transmitted to a host through the blood meal of an infected Ixodes tick. This bacterial infection represents the most common vector-borne human disease in the northern hemisphere and can present with a variety of focal and non-focal symptoms and signs. Lyme disease is divided into three stages: early localized, early disseminated, and late stage. In patients who have not been treated with antibiotics, different clinical manifestations can occur in each stage of infection. Furthermore, the stages can overlap and, in some cases, late manifestations can be the presenting feature. In the majority of patients, the infection is cured after antibiotic treatment, while in a subset of cases, chronic health problems may persist for months and years. To date, the treatment of these persistent symptoms, defined as post-treatment Lyme disease (PTLD), is not well-understood and still remains the subject of a great deal of scientific dispute and controversy within the medical community. In the USA, the annual costs associated with Lyme disease and PTLD are estimated to be between USD 712 million and USD 1.3 billion. This Special Issue will provide an overview of all potential specific and non-specific manifestations of Lyme disease in children and the adult population. In addition, it will include papers that describe advances and potential challenges in further understanding the pathophysiology, diagnosis, and treatment of Lyme disease at molecular and clinical levels.
Potential topics include, but are not limited to:
- Historical overview of Lyme disease
- Molecular and immune aspects of Lyme disease
- Lyme carditis
- Borrelial lymphocytoma
- Lyme arthritis
- Dermatological manifestations of Lyme borreliosis
- Psychiatric disorders related to Lyme disease
- Nonspecific manifestations of Lyme disease that have been reported in other organ systems (e.g., ocular Lyme Borreliosis and vasculitis)
Dr. Stefan D. Momčilović
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- clinical manifestations
- pathophysiological mechanisms
- molecular mechanisms
- post-treatment Lyme disease