Submit to Special Issue Submit Abstract to Special Issue Review for JPM Propose a Special Issue

Journal Menu

Journal Browser

Special Issue "Multidisciplinary Therapeutic Strategies in Head and Neck Surgery"

Special Issue Editors
Special Issue Information
Keywords
Published Papers

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 27 February 2024 | Viewed by 8191

Share This Special Issue

Special Issue Editors

Dr. Salvatore Crimi

E-Mail Website
Guest Editor

Maxillo Facial Unit, University Hospital “Policlinico San Marco” of Catania, 95124 Catania, Italy
Interests: oral surgery; oral cancers; head and neck cancers; cutaneous lesions; head and neck trauma
Special Issues, Collections and Topics in MDPI journals

Prof. Dr. Gabriele Cervino

E-Mail Website
Guest Editor

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina-Policlinico "Gaetano Martino”, Via Consolare Valeria, 98100 Messina, Italy
Interests: biomaterials; oral surgery; implantology; oral pathology; prosthodontics; bioengineering
Special Issues, Collections and Topics in MDPI journals

Dr. Riccardo Nocini

E-Mail Website
Guest Editor

Unit of ENT, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy
Interests: head and neck microsurgery; piezoelectric surgery; otolaryngology procedures; craniofacial malformations; head and neck microsurgery; sleep apnea syndrome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Due to its anatomical complexity, head and neck surgery is increasingly becoming a multidisciplinary pathology. Because of the multifunctional anatomical intricacies of the head and neck, disease progression and therapy-related side effects often severely affect the patient’s appearance and self-image, as well as their ability to breathe, speak, and swallow. In present times, head and neck pathologies require a combination of multiples specialties working together, from the easy and basic affections of the oral cavity (such as odontogenic cyst, rhinosinusitis, dentofacial malformation, OSAS, and MRONJ) to more complex situations, such as epithelial malignancies of the upper aerodigestive tract (nasal cavity, oral cavity, oropharynx, pharynx, hypopharynx, and larynx), cutaneous malignancies of the head and neck region, and malignant tumors arising from different cell types of the thyroid and salivary glands, as well as simple and complex traumas. The enlistment of patients involves various specialists, such us oral surgeons, maxillofacial surgeons, head and neck surgeons, and dermatologists, as well as prosthodontists. An aim of providing the final recovery of aesthetics and functions throughout a close cooperation of different medical specialists should be a requirement of head and neck surgery. It is almost of gold standard that these patients need personalized treatment strategies involving all the mentioned specialties in a multidisciplinary approach. These factors make both head and neck surgery and its management especially difficult for patients, as well as motivating us to develop the field forward to create a “tailor made” solution from a multidisciplinary perspective.

Areas in particular need of novel insights include the treatment of recurrent and metastatic disease and the personalization of treatment based on the molecular characteristics of individual tumors.

For the above reasons, in this Special Issue, we welcome clinical research papers, basic translational professional opinions, and reviews in the broad field of multidisciplinary therapeutic surgical and rehabilitative strategies in head and neck surgery.

Dr. Salvatore Crimi
Prof. Dr. Gabriele Cervino
Dr. Riccardo Nocini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

head and neck surgery
oral surgery
multidisciplinary approach
Oral Maxillo Facial surgery
Rehabilitative strategies
oral oncology
oral cancers
trauma
ENT durgery
OSAS
dento-facial deformities
orthognatic surgery

Published Papers (7 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

Jump to: Review, Other

13 pages, 3593 KiB

Open AccessArticle

Pretreatment Tumor Volume and Tumor Sphericity as Prognostic Factors in Patients with Oral Cavity Squamous Cell Carcinoma: A Prospective Clinical Study in 95 Patients

and

J. Pers. Med. 2023, 13(11), 1601; https://doi.org/10.3390/jpm13111601 - 13 Nov 2023

Viewed by 440

Abstract

The prognostic impact of tumor volume and tumor sphericity was analyzed in 95 patients affected by oral cancer. The pre-operative computed tomography (CT) scans were used to segment the tumor mass with threshold tools, obtaining the corresponding volume and sphericity. Events of recurrence and tumor-related death were detected for each patient. The mean follow-up time was 31 months. A p-value of 0.05 was adopted. Mean tumor volume resulted higher in patients with recurrence or tumor-related death at the Student’s t-test (respectively, 19.8 cm³ vs. 11.1 cm³, p = 0.03; 23.3 cm³ vs. 11.7 cm³, p = 0.02). Mean tumor sphericity was higher in disease-free patients (0.65 vs. 0.59, p = 0.04). Recurrence-free survival and disease-specific survival were greater for patients with a tumor volume inferior to the cut-off values of 21.1 cm³ (72 vs. 21 months, p < 0.01) and 22.4 cm³ (85 vs. 32 months, p < 0.01). Recurrence-free survival and disease-specific survival were higher for patients with a tumor sphericity superior to the cut-off value of 0.57 (respectively, 49 vs. 33 months, p < 0.01; 56 vs. 51 months, p = 0.01). To conclude, tumor volume and sphericity, three-dimensional parameters, could add useful information for better stratification of prognosis in oral cancer. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

12 pages, 2882 KiB

Open AccessArticle

Does Age Affect the Rate of Spinal Nerve Injury after Selective Neck Dissection? Age as a Prognostic Factor of Spinal Nerve Injury after Selective Neck Dissection

and

J. Pers. Med. 2023, 13(7), 1082; https://doi.org/10.3390/jpm13071082 - 29 Jun 2023

Viewed by 1108

Abstract

Objective: The objective of this study is to investigate whether age is a significant risk factor for spinal nerve injury following selective neck dissection (SND) in patients with head and neck cancer. Methods: A retrospective cohort study was conducted on patients who had undergone SND for head and neck cancer at a tertiary hospital between 2020 and 2022. The primary outcome was the incidence of spinal nerve injury after SND. The secondary outcomes included the types and severity of spinal nerve injury and the impact of age on these outcomes. Results: A total of 78 patients were included in the study and subdivided into two groups. Two shoulder-specific questionnaires (the Shoulder Pain and Disability Index (SPADI) and the Shoulder Disability Questionnaire (SDQ)) were administered to assess shoulder morbidity postoperatively. Twelve patients showed shoulder impairment following surgery. We divided the sample into two age-based groups; the older group showed a higher rate of SAN injury and the younger group showed a lower rate of improvement over time. Conclusion: This study suggests that age is a significant risk factor for spinal nerve injury following SND in patients with head and neck cancer. Older patients are more likely to experience spinal nerve injury after SND than younger patients. The findings of this study may help in the development of strategies to prevent spinal nerve injury in older patients undergoing SND for head and neck cancer. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

10 pages, 1443 KiB

Open AccessArticle

Is Beauty a Matter of Volume Distribution? Proposal of a New Aesthetic Three-Dimensional Guide in Orthognathic Surgery

and

J. Pers. Med. 2023, 13(6), 936; https://doi.org/10.3390/jpm13060936 - 01 Jun 2023

Cited by 2 | Viewed by 879

Abstract

Background: Orthognathic surgery is a multidisciplinary surgery in which the aesthetic results have become increasingly important, and consequently, also the predictability of the surgical outcomes. In this paper, we analyzed the volumetric distribution of the lower two-thirds of the face, in patients operated by orthognathic surgery and selected for their attractiveness. Our goal was to analyze the aesthetic volumetric distribution for gender and to propose our operating philosophy, that a normative distribution of facial volumes could be used like a new 3D aesthetic guide in orthognathic planning. Methods: A group of 46 orthognathic patients (26 females, 20 males) with the best postoperative aesthetic score was selected by a jury of plastic surgeons, orthodontists, and journalists. The mean soft tissue volumes of the malar, maxillary, mandibular, and chin regions were analyzed. Results: Overall, we measured a mean female facial volume distribution of 38.7%, 29%, 27.6%, and 4.7%, respectively, in the malar, maxillary, mandibular, and chin regions, while in males, it was 37%, 26%, 30%, and 6%, respectively. Conclusions: In this paper, the expansion of facial volumes in orthognathic surgery is proposed as a key point for facial harmonization. Beauty could be scientifically interpreted as a balanced distribution of facial volumes, and the virtual study of this distribution can become an important part of the preoperative analysis, such as a “volumetric” 3D cephalometry, where the surgeon could use average values of aesthetic volumetric distribution as preoperative surgical references. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

14 pages, 7438 KiB

Open AccessArticle

Tongue Reconstruction with Buccinator Myomucosal Island Flaps: Technical Considerations, Oncologic Safety, Functional Outcomes and QoL Assessment—A Retrospective Observational Study

and

J. Pers. Med. 2023, 13(6), 879; https://doi.org/10.3390/jpm13060879 - 23 May 2023

Cited by 1 | Viewed by 1220

Abstract

The objective of this study was to investigate the effectiveness of buccinator myomucosal island flaps for tongue reconstruction following malignant tumor resections. A retrospective study was performed on 52 patients who underwent tongue reconstructions with buccinator myomucosal island flaps between 2012 and 2020. We reviewed the flap type and size, harvesting time, recipient- and donor-site complications, postoperative oncologic outcomes, functional recovery and QoL assessment. All of the flaps were transposed successfully without any total flap loss. Neither in the primary site nor in the neck were cancer relapses observed. An evaluation of the sensitivity revealed that 96.1% of patients experienced a recovery of touch, two-point and pain sensations. There were significant differences between the flap and the native mucosa in terms of the tactile (p < 0.001), pain (p < 0.001) and two-point (p < 0.001) thresholds. The average swallowing score recorded was 6.1 out of 7, with only minor complaints. The quality of life assessments demonstrated high scores across physical (24.5 out of 28), social (25.8 out of 28), emotional (20.3 out of 24) and functional (25 out of 28) aspects. The present study showed how buccinator myomucosal island flaps represent an effective and functional tongue reconstructive option, requiring a short operative time with a low rate of donor site morbidity, and with evidence of long-term oncologic safety and high quality of life. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

12 pages, 1056 KiB

Open AccessFeature PaperArticle

A Single-Center Retrospective Analysis of 14 Head and Neck AVMs Cases Treated with a Single-Day Combined Endovascular and Surgical Approach

and

J. Pers. Med. 2023, 13(5), 757; https://doi.org/10.3390/jpm13050757 - 28 Apr 2023

Viewed by 1530

Abstract

Arteriovenous malformations (AVMs) are rare congenital defects of vascular development whose treatment remains challenging. The paper presents a retrospective single-center study of 14 patients with AVMs of the head and neck region undergoing combined endovascular and surgical treatment in a single day. AVM architecture and therapeutic strategies were determined on the basis of angiographic studies, while the psychological involvement of each patient was assessed by means of a questionnaire. Most of the 14 patients achieved satisfactory clinical results with no recurrences, good aesthetic and functional results, and most patients reported improved quality of life. The combined endovascular and surgical approach is an effective treatment for AVMs of the head and neck and performing it on the same day is a possible option often accepted by patients which guarantees operative advantages for the surgeon. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

Review

Jump to: Research, Other

11 pages, 548 KiB

Open AccessReview

Surgery for Port-Wine Stains: A Systematic Review

and

J. Pers. Med. 2023, 13(7), 1058; https://doi.org/10.3390/jpm13071058 - 28 Jun 2023

Viewed by 861

Abstract

Background: Port-wine stains (PWS) are congenital low-flow vascular malformations of the skin. PWS tend to become thicker and darker with time. Laser therapy is the gold standard and the first-line therapy for treating PWS. However, some resistant PWS, or PWS that have tissue hypertrophy, do not respond to this therapy. Our aim is to evaluate the role of surgery in the treatment of PWS birthmarks. Methods: A literature search was performed in PubMed, Scopus, Web of Science (WOS) and Google Scholar for all papers dealing with surgery for port-wine stains, from January 2010 to December 2020 using the search strings: (capillary vascular malformation OR port-wine stains OR Sturge Weber Syndrome OR sws OR pws) AND (surgical OR surgery). Results: Ten articles were identified and used for analysis. They were almost all case series with a short follow up period and lacked an objective–systematic score of evaluation. Conclusions: Delay in treatment of port wine stains may result in soft tissue and bone hypertrophy or nodules with disfiguring or destructive characteristics. The correction of PWS-related facial asymmetry often requires bone surgery followed by soft tissue corrections to achieve a more harmonious, predictable result. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Figure 1

Other

Jump to: Research, Review

11 pages, 670 KiB

Open AccessSystematic Review

Multiple General Anesthesia in Children: A Systematic Review of Its Effect on Neurodevelopment

and

J. Pers. Med. 2023, 13(5), 867; https://doi.org/10.3390/jpm13050867 - 21 May 2023

Cited by 1 | Viewed by 1543

Abstract

The effect of multiple general anesthesia (mGA) procedures administered in early life is a critical theme and has led the Food and Drug Administration (FDA) to issue an alert. This systematic review seeks to explore the potential effects on neurodevelopment of mGA on patients under 4 years. The Medline, Embase and Web of Science databases were searched for publications up to 31 March 2021. The databases were searched for publications regarding “children multiple general anesthesia OR pediatric multiple general anesthesia”. Case reports, animal studies and expert opinions were excluded. Systematic reviews were not included, but they were screened to identify any possible additional information. A total of 3156 studies were identified. After removing the duplicates, screening the remaining records and analyzing the systematic reviews’ bibliography, 10 studies were considered suitable for inclusion. Comprehensively, a total cohort of 264.759 unexposed children and 11.027 exposed children were assessed for neurodevelopmental outcomes. Only one paper did not find any statistically significant difference between exposed and unexposed children in terms of neurodevelopmental alterations. Controlled studies on mGA administered before 4 years of age support that there might be a greater risk of neurodevelopmental delay in children receiving mGA, warranting the need for careful risk/benefit considerations. Full article

(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)

► Show Figures

Journal Menu

Journal Browser

Special Issue "Multidisciplinary Therapeutic Strategies in Head and Neck Surgery"

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Published Papers (7 papers)

Research

Review

Other

Further Information

Guidelines

MDPI Initiatives

Follow MDPI