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Prediction and Treatment of Perioperative Infection in Urinary Stones Surgery
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Special Issue "Prediction and Treatment of Perioperative Infection in Urinary Stones Surgery"

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: closed (10 June 2023) | Viewed by 1020

Special Issue Editors

Prof. Dr. Yunfei Xu

E-Mail Website
Guest Editor
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China
Interests: urinary tract infection; urinary stones; tumors of the urinary system
Prof. Dr. Baojun Gu
E-Mail Website
Guest Editor
Department of Urology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200235, China
Interests: neurourology and urodynamics
Dr. Tiancheng Xie
E-Mail Website
Guest Editor
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China
Interests: urinary stones; andrology

Special Issue Information

Dear Colleagues, 

Perioperative infection arising from urolithiasis is a major challenge for urologists. Urolithiasis is often accompanied by urinary tract obstruction and hydronephrosis, susceptibility to urinary tract infection, and the development of urogenic sepsis due to aggravation caused by urinary tract obstruction. There are many factors that affect perioperative infection arising from urinary tract stones, so urologists must take care to prevent the occurrence of inflammation. Additionally, given the current lack of novel biomarkers for the prediction of perioperative infection arising from urinary tract stone surgery, we aim to explore current methods of prediction, prevention and treatment based on the latest research. Through this, we hope to provide urologists with the knowledge to treat urinary tract stones and accompanying urinary tract infections.

Prof. Dr. Yunfei Xu
Prof. Dr. Baojun Gu
Dr. Tiancheng Xie
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urinary stones
  • anti-inflammatory
  • surgery
  • perioperative infection
  • sepsis
  • SOFA

Published Papers (1 paper)

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Research

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Article
The Relationship between Preoperative Urine Culture and Post-Percutaneous Nephrostolithotomy Systemic Inflammatory Response Syndrome: A Single-Center Retrospective Study
by
Hongmin Zhou
,
Tiancheng Xie
,
Yuchen Gao
,
Xudong Yao
and
Yunfei Xu
J. Pers. Med. 2023, 13(2), 187; https://doi.org/10.3390/jpm13020187 - 20 Jan 2023
Viewed by 804
Abstract
Background: To predict the occurrence of systemic inflammatory response syndrome (SIRS) after percutaneous nephrostrolithotomy(PCNL), preoperative urine culture is a popular method, but the debate about its predictive value is ongoing. In order to better evaluate the value of urine culture before percutaneous nephrolithotomy, [...] Read more.
Background: To predict the occurrence of systemic inflammatory response syndrome (SIRS) after percutaneous nephrostrolithotomy(PCNL), preoperative urine culture is a popular method, but the debate about its predictive value is ongoing. In order to better evaluate the value of urine culture before percutaneous nephrolithotomy, we conducted a single-center retrospective study. Methods: A total of 273 patients who received PCNL in Shanghai Tenth People’s Hospital from January 2018 to December 2020 were retrospectively evaluated. Urine culture results, bacterial profiles, and other clinical information were collected. The primary outcome observed was the occurrence of SIRS after PCNL. Univariate and multivariate logistic regression analysis was performed to determine the predictive factors of SIRS after PCNL. A nomogram was constructed using the predictive factors, and the receiver operating characteristic (ROC) curves and calibration plot were drawn. Results: Our results showed that there was a significant correlation between positive preoperative urine cultures and the occurrence of postoperative systemic inflammatory response syndrome. Meanwhile, diabetes, staghorn calculi, and operation time were also risk factors for postoperative systemic inflammatory response syndrome. Our results suggest that among the positive bacteria in urine culture before percutaneous nephrolithotomy, Enterococcus faecalis has become the dominant strain. Conclusion: Urine culture is still an important method of preoperative evaluation. A comprehensive evaluation of multiple risk factors should be undertaken and heeded to before percutaneous nephrostrolithotomy. In addition, the impact of changes in bacterial drug resistance is also worthy of attention. Full article
(This article belongs to the Special Issue Prediction and Treatment of Perioperative Infection in Urinary Stones Surgery)
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