Special Issue "Recent Advances in Personalized Cervical Cancer Screening"

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (20 June 2023) | Viewed by 2977

Special Issue Editors

Department of Research, Cancer Registry of Norway, Oslo, Norway
Interests: HPV; cervical cancer; cervical screening; HPV genotyping; HPV vaccination; cancer
Department of Research, Cancer Registry of Norway, Oslo, Norway
Interests: human papillomavirus (HPV); epidemiologic studies; cervical cancer; cancer epidemiology; epidemiological modeling; epidemiologic methods; cervical cancer screening

Special Issue Information

Dear Colleagues,

A large majority of cervical cancer (more than 95%) is due to the human papillomavirus (HPV). The risk of disease progression and cancer is highly dependent on HPV genotype, and the use of HPV genotyping is increasingly finding its way into cervical screening programs.

The detailed genotyping information allows for an improved risk stratification, where women are approached and treated according to the risk they run. A great challenge remains, however, regarding how risk-based screening should be implemented in organized screening programs. This implementation should be tailored to the setting where HPV vaccinated cohorts are entering the screening programs. In addition, there are several recent developments related to cervical screening, as self-sampling, urine sampling and the use of methylation markers, that promise important parts of the screening programs.

This Special Issue aims to provide researchers with an opportunity to publish both original research and review articles related to methods for improved and more personalized cervical cancer and pre-cancer predictions based on the increasing amount of relevant information, including HPV genotyping, HPV vaccination information, and data from more recent methodologies for cervical cancer screening. 

Dr. Ståle Nygård
Dr. Mari Nygård
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HPV
  • cervical cancer
  • cervical screening
  • HPV genotyping
  • HPV vaccination
  • personalized medicine

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Editorial

Jump to: Research

Editorial
The Future of Cervical Cancer Prevention: From “One-Size-Fits-All” to Personalized Screening
J. Pers. Med. 2023, 13(2), 161; https://doi.org/10.3390/jpm13020161 - 17 Jan 2023
Cited by 1 | Viewed by 1457
Abstract
Cervical cancer screening represents an excellent model system for the development of personalized cancer-prevention strategies [...] Full article
(This article belongs to the Special Issue Recent Advances in Personalized Cervical Cancer Screening)

Research

Jump to: Editorial

Article
Analysis of HR-HPV Infection Concordance Rates in Cervical and Urine Specimens; Proposal of Additional Cervical Screening Process for Women Who Refuse Invasive Cervical Sampling
J. Pers. Med. 2022, 12(12), 1949; https://doi.org/10.3390/jpm12121949 - 24 Nov 2022
Cited by 1 | Viewed by 1120
Abstract
This study aimed to provide basic data for the clinical application of urine samples to prevent cervical cancer due to persistent HR-HPV infection in women who refuse invasive cervical sampling. Pairs of cervical swabs and urine samples were collected from 210 asymptomatic women [...] Read more.
This study aimed to provide basic data for the clinical application of urine samples to prevent cervical cancer due to persistent HR-HPV infection in women who refuse invasive cervical sampling. Pairs of cervical swabs and urine samples were collected from 210 asymptomatic women who visited the obstetrics and gynecology department from August to December 2020, and a total of 420 samples were collected. Using the PANA RealTyper™ HPV Screening Kit as a real-time PCR method, paired cervical swabs and random urine samples were tested. A total of 19 samples (9.1%) were both HPV positive and 177 (84.3%) were both negative. The concordance between the two types of samples was 93.3%, with κ = 0.69 (moderate, 95% CI 0.54–0.84). The HPV infection rate by age was highest in both cervical swabs and urine samples in women in their 30s, followed by those in their 20s. Thus, the HPV infection rate was high in young women under 40 at 69.2% in cervical swabs and 61.8% in urine samples. Urine samples are considered a valuable screening test for women who refuse invasive Pap tests to prevent cervical cancer caused by persistent HPV infection. Full article
(This article belongs to the Special Issue Recent Advances in Personalized Cervical Cancer Screening)
Show Figures

Graphical abstract

Back to TopTop