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Special Issue "Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders"

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A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (20 June 2023) | Viewed by 3967

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Special Issue Editors

Dr. Federica Di Spirito

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Guest Editor

Department of Medicine and Surgery, University of Salerno, 84084 Baronissi, Italy
Interests: oral medicine and interconnected systemic disorders; oral microbiome, dysbiosis and interconnected systemic disorders; periodontology and implantology; applied technologies (disease prevention, teledentistry, machine learning in dentistry education)
Special Issues, Collections and Topics in MDPI journals

Dr. Alessandra Amato

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Guest Editor

Department of Neuroscience, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, Italy
Interests: general dentistry; pedodontics; orthodontics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Several conditions, pathologies, and disorders affect the soft and hard tissues of the oral cavity, as well as the temporomandibular joints and occlusion, thus potentially affecting oral functions, patient quality of life, and general health. Some of these may also constitute risk factors for general health disruption through different mechanisms, and share common etiology with systemic diseases. A better understanding of the risk factors and the underlying pathogenic mechanisms may aid in developing personalized preventive strategies to be combined with population-based ones. Moreover, focused evaluation of case-specific risk/benefit ratio and investigations on patient-centered care may encourage the provision of personalized therapeutic approaches as part of multidisciplinary care.

Research papers, reviews, commentaries, and conference papers are welcomed in this Special Issue.

Dr. Federica Di Spirito
Dr. Alessandra Amato
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

oral health
systemic conditions
disorders
diseases
stomatitis
mucositis

Published Papers (4 papers)

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Editorial

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Open AccessEditorial

Integrating P4 Medicine in Teledentistry and M-Health in Oral, Dental, and Periodontal Care

Federica Di Spirito

J. Pers. Med. 2023, 13(1), 111; https://doi.org/10.3390/jpm13010111 - 04 Jan 2023

Cited by 3 | Viewed by 974

Abstract

Given that dental practice is currently based on the “average” patient, providing therapeutic and rehabilitative interventions rather than preventive measures [...] Full article

(This article belongs to the Special Issue Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders)

Open AccessEditorial

Personalized Oral and Dental Care

Alessandra Amato

J. Pers. Med. 2023, 13(1), 110; https://doi.org/10.3390/jpm13010110 - 04 Jan 2023

Viewed by 1111

Abstract

Recent advances in genomics, data analytics technologies, and biotechnology have been unprecedented, ushering in a new era of healthcare in which interventions are increasingly tailored to individual patients [...] Full article

(This article belongs to the Special Issue Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders)

Research

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Open AccessArticle

Systemic and Oral Health Parameters in Eutrophic and Overweight/Obese Adolescents: A Cross-Sectional Study

Alessandro Mastroianni

Leonzio Fortunato

Amerigo Giudice

and

Mario Migliario

J. Pers. Med. 2023, 13(7), 1073; https://doi.org/10.3390/jpm13071073 - 29 Jun 2023

Viewed by 495

Abstract

To date, studies focusing on oral health in obese adolescents have provided controversial data. The aim of this cross-sectional study was to investigate systemic and oral health parameters in eutrophic and overweight/obese adolescents. In total, 100 adolescents, mean aged 13.33 ± 2.04 years, were divided into two groups: 59 overweight/obese adolescents in the study group (SG) and 41 eutrophic-weight adolescents in the control group (CG). Chi-squared and Fisher exact tests were performed to compare dichotomous and categorical variables between the two groups. The subjects in the SG (mean aged 13.21 ± 2.21) reported a body mass index (BMI) of 29.05 ± 4.09 kg/m², corresponding to over 95° percentile for both genders, and the subjects in the CG (mean aged 13.49 ± 1.77) reported a BMI of 18.26 ± 4.81 kg/m², corresponding to 25° percentile for both genders. In the SG, the serum level of 25-hydroxy-vitamin D was significantly lower (p-value < 0.001), whereas fasting blood glucose (p = 0.006), waist circumference, and hip circumference were significantly higher (p-value < 0.001). Plaque Index (PI), Plaque Control Record (PCR), Oral Hygiene Index (OHI), Gingival Index (GI), and Gingival bleeding index (GBI) depicted a significantly worse level of oral health in the SG. Moreover, the number of subjects with caries was significantly higher in the SG. Nutritional and physical activity status according to the Mediterranean Diet Quality Index for children and teenagers (KIDMED test) and the International Physical Activity Questionnaire (IPAQ-Adolescent) were reported to be significanlty better in the CG. In light of our results, obesity and poor oral health coexist in a cohort of adolescents. A screening of oral health status should be considered in obese subjects to focus resources on therapeutic interventions aiming at improving oral health. Full article

(This article belongs to the Special Issue Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders)

Review

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Open AccessReview

Human Monkeypox: Oral Implications and Recommendations for Oral Screening and Infection Control in Dental Practice

and

J. Pers. Med. 2022, 12(12), 2000; https://doi.org/10.3390/jpm12122000 - 02 Dec 2022

Cited by 4 | Viewed by 1016

Abstract

The World Health Organization declared the spread of the human monkeypox virus (MPXV) an “emerging threat of moderate health concern” on 23 June 2022. Although about 20,000 cases of Monkeypox (MPX) were recorded in Europe and more than 28,000 in the United States from May to October 2022, their number is still small compared to the number of dental patients treated annually. Therefore, the likelihood of oral healthcare workers encountering an MPX case is relatively low in not endemic regions. In addition, MPX-positive individuals are considered contagious only during the prodromal or acute phase. However, the exact shedding and transmission routes of MPX and the associated risk of transmission in the dental setting remain unclear. Moreover, infected subjects whose disease is confined to the head and neck may require oral and dental care because they complain of lymphadenopathy involving the cervical lymph nodes. Furthermore, MPX lesions may first appear in the oral cavity or perioral area. Therefore, given the recent spread of MPXV in non-endemic areas where dentists are not used to considering this disease in the differential diagnosis and taking appropriate preventive measures, all oral healthcare providers nowadays should be aware of the oral presentation of MPX for adequate oral screening and appropriate preventive measures for infection control in the dental practice. Full article

(This article belongs to the Special Issue Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders)

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Special Issue "Personalized Medicine to Oral Pathologies and Systemic Interconnected Conditions, Diseases, and Disorders"

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