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The Challenges and Therapeutic Prospects in Chronic Pain
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Special Issue "The Challenges and Therapeutic Prospects in Chronic Pain"

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 5567

Special Issue Editor

Dr. Lisa Goudman

E-Mail Website
Guest Editor
1. STIMULUS Research Group, Vrije Universiteit Brussel, Brussels, Belgium
2. Department of Neurosurgery, Universitair Ziekenhuis Brussel, Brussels, Belgium
3. Research Foundation—Flanders (FWO), Brussels, Belgium
Interests: neuromodulation; persistent spinal pain syndrome; chronic pain; statistics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The subjective and personal experience of pain itself, combined with the multidimensional output mechanisms of chronic pain and the broad range of potential treatment options, all contribute to the complexity of chronic pain management. This makes it difficult to provide an individual patient with effective but generalized treatment.

The first part of this Special Issue will explore the challenges that clinicians encounter when treating patients with chronic pain, as well as the identification of individual markers in chronic pain patients, which are involved in alleviating the personal burden. Secondly, promising new therapeutic targets for personalized therapies in chronic pain management can be discussed.

Several developments within the field of chronic pain were implemented to increase patients’ quality of life and obtain pain relief. These include remote consultations, individually tailored psychological self-management programs or personalized prescription of opioid analgesics. Additionally, explorations of chronic pain biomarkers have continued to expand with the ultimate goal of finding treatment markers for chronic pain, regardless of the exact underlying pathology, and potentially emphasising new therapeutic prospects.

Clinical perspectives, high-standard qualitative research or original articles elaborating on the difficulties and challenges of current chronic pain management will be considered for this Special Issue. Manuscripts that address new potential diagnostic tools and therapeutic approaches and algorithms for personalized care in chronic pain management are also welcome. Both clinical and pre-clinical research papers and systematic reviews (potentially including a meta-analysis) are within the scope of this Special Issue.

Dr. Lisa Goudman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • precision medicine
  • chronic pain management
  • personalized care
  • therapeutic targets for chronic pain

Published Papers (3 papers)

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Research

11 pages, 653 KiB  
Article
Goals, Expectations, and the Definition of Success for Neuromodulation for Pain According to Representatives of Neuromodulation Device Manufacturers
by
Maarten Moens
,
William Alliet
,
Maxime Billot
,
Ann De Smedt
,
Panagiotis Flamée
,
Domien Vanhonacker
,
Manuel Roulaud
,
Philippe Rigoard
and
Lisa Goudman
J. Pers. Med. 2022, 12(9), 1457; https://doi.org/10.3390/jpm12091457 - 06 Sep 2022
Viewed by 1057
Abstract
Representatives of neuromodulation device manufacturers are expected to facilitate the relationship between patients and healthcare providers. Nevertheless, the goals, expectations, and definition of success for neuromodulation for pain have not yet been explored. Representatives present at the 2nd Joint Congress of the INS [...] Read more.
Representatives of neuromodulation device manufacturers are expected to facilitate the relationship between patients and healthcare providers. Nevertheless, the goals, expectations, and definition of success for neuromodulation for pain have not yet been explored. Representatives present at the 2nd Joint Congress of the INS European Chapters in September 2021 completed a survey to ascertain their opinions about the goals to achieve with neuromodulation, the factors that they expect to change, and their definition of success for neuromodulation. In total, 39 representatives completed the survey. To provide excellent service for patients (22.4%), to become a trusted partner for physicians (21.5%), and to provide excellent service for physicians (20.7%) were the highest ranked goals. The most frequently reported factors that were expected to change were pain intensity (23.1%), patient satisfaction (19.7%), mobility/functioning (14.5%), and capacity to return to work (13.7%). Within the definitions of success, increased quality of life of the patient was stated in 21% of the definitions, closely followed by pain control (19.3%) and happiness/patient satisfaction (15.8%). The goals of representatives of neuromodulation device manufacturers seem to focus on ensuring a good relationship with physicians on the one hand and providing good service towards patients on the other hand, whereby pain control, quality of life, and patient satisfaction seem to be important for company representatives. Full article
(This article belongs to the Special Issue The Challenges and Therapeutic Prospects in Chronic Pain)
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13 pages, 2479 KiB  
Article
The Adjuvant Therapy of Intravenous Laser Irradiation of Blood (ILIB) on Pain and Sleep Disturbance of Musculoskeletal Disorders
by
(Jimmy) Chun-Ming Fu
,
Nai-Kuang Wang
,
Yuan-Yang Cheng
and
Shin-Tsu Chang
J. Pers. Med. 2022, 12(8), 1333; https://doi.org/10.3390/jpm12081333 - 19 Aug 2022
Cited by 4 | Viewed by 2024
Abstract
(1) Background: Musculoskeletal pain is both intractable and irritating. Intravenous Laser Irradiation of Blood (ILIB) therapy has been used as pain control treatment for this condition. However, there remains a lack of clear evidence regarding ILIB on pain control. This study aimed to [...] Read more.
(1) Background: Musculoskeletal pain is both intractable and irritating. Intravenous Laser Irradiation of Blood (ILIB) therapy has been used as pain control treatment for this condition. However, there remains a lack of clear evidence regarding ILIB on pain control. This study aimed to reveal the result of changes in patient pain intensity after receiving ILIB therapy. (2) Methods: We conducted a retrospective analysis of pain scores and sleep quality from 76 patients diagnosed with musculoskeletal disease who received three courses of ILIB therapy. Each course included ten sessions of ILIB treatment over ten consecutive days. During ILIB therapy, patients were inserted with a laser fiber optic needle which irradiated blood cells via a 632.8 nm Helium-Neon laser light over a period of 60 min. Pain scores were evaluated using the Visual Analogue Scale (VAS), whereas sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI). These scores would be recorded both before and after each ILIB treatment course. (3) Results: The mean of all patients’ initial VAS score was 5.35. After completing three courses of ILIB treatment, the mean VAS score decreased to 2.2, which indicated a significant reduction in pain intensity. Additionally, patients experienced sleep quality improvement levels from PSQI 8.97 to 5.53 upon completion of three courses of ILIB treatment. (4) Conclusions: Intravenous Laser Irradiation of Blood (ILIB) resulted in a positive pain control effect on patients with musculoskeletal disease, especially for those with moderate to severe pain intensity (initial VAS score >4). Additionally, patients experienced better sleep quality as a result of their pain relief after receiving ILIB treatment. Full article
(This article belongs to the Special Issue The Challenges and Therapeutic Prospects in Chronic Pain)
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9 pages, 1799 KiB  
Article
Social Media and Chronic Pain: What Do Patients Discuss?
by
Lisa Goudman
,
Ann De Smedt
and
Maarten Moens
J. Pers. Med. 2022, 12(5), 797; https://doi.org/10.3390/jpm12050797 - 14 May 2022
Cited by 4 | Viewed by 1948
Abstract
A high number of online support groups have been created on social media platforms to reinforce personal empowerment and social support. The goal of this study was to perform natural language processing by constructing a bag-of-words model and conducting topic modelling based on [...] Read more.
A high number of online support groups have been created on social media platforms to reinforce personal empowerment and social support. The goal of this study was to perform natural language processing by constructing a bag-of-words model and conducting topic modelling based on posts extracted from a chronic pain community. The subreddit called ‘r/sChronicPain’ was used to investigate communication on social media platforms for chronic pain patients. After data cleaning and lemmatisation, a word cloud was constructed, and the most frequent words and most frequent body regions were counted. Latent Dirichlet allocation was used to perform topic modelling. In the final analysis set, 937 unique posts were included. The most frequent word was ‘pain’, followed by ‘doctor’, ‘day’, ‘feel’, ‘back’, ‘year’, and ‘time’. Concerning the body regions, ‘back’ was most often mentioned, followed by ‘neck’ and ‘leg’. Based on coherence scores, one topic was extracted with ‘pain’ as the keyword with the highest weight. In line with the allocation of chronic low-back pain as a major health problem and increasing prevalence, back pain was most often mentioned. It seems that the primarily treatment trajectories that are proposed by medical physicians are discussed on social media, compared to interventions by other healthcare providers. Full article
(This article belongs to the Special Issue The Challenges and Therapeutic Prospects in Chronic Pain)
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