Role of Nano-Bio Interaction for Nanotheranostic Applications

A special issue of Journal of Nanotheranostics (ISSN 2624-845X).

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 4846

Special Issue Editors

Kalinga Institute of Industrial Technology, Bhubaneswar, Odisha 751024, India
Interests: green nanobiotechnology; nano-bio interaction; nanotoxicology; nanomedicine
Special Issues, Collections and Topics in MDPI journals
Adolphe Merkle Institute, Université de Fribourg,1700 Fribourg, Switzerland
Interests: in vitro toxicity; hazard assessment; nanomedicine; bionanomaterials; nano-bio particle interaction
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanomaterials have got special attention from the scientific and industrial community due to their growing applications in different fields. Recently the area of application of nanomaterials has reached a core level of the biomedical field like drug delivery and diseases diagnostics. Moreover, owing to the peculiar physical and biological properties of nanomaterials, the nanomaterials can be modified and functionalized for biomedical applications.

With the advancement in nanotechnology and nanomaterials applications, researchers are trying to explore the different technologies for the utilization of different nanomaterials for theranostic applications like inhibition of microbial infections, diagnostic of different diseases markers, use of nano-conjugates for marker development in diseases diagnostic processes, however, a detailed understanding is required to understand the nano-bio interactions at the cellular and molecular level to excavate the mechanism of the phenomenon. The understanding of the cellular and molecular interactions will provide the pathway for exploring the nano-biocompatibility for different applications which is the must criterion for the implication of any nanomaterials for biomedical applications.

This Special Issue calls for a spectrum of studies in the field of nanotechnology which are poised to carry out the intrinsic and detailed research of nanomaterials- biological interaction for different biomedical and nanotheranostic applications. The information will be helpful for discovering new findings in the field of nanomaterial science for theranostic applications.

We invite manuscripts that entail a wide range of issues and concerns regarding nanomaterial properties, and their cellular and molecular interaction with biological entities, including but not limited to:

  • Newly synthesized nanomaterials for theranostic applications.
  • Mechanistic investigation of the interaction of different types of nanomaterials in vitro and in vivo atmospheres.
  • Functionalization and modification of nanomaterials properties for their biological impact on cellular uptake and physiological processes.

Dr. Suresh K. Verma
Dr. Sandeep Keshavan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Nanotheranostics is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nano-bio interaction
  • nanomaterials
  • nanomedicine
  • theranostic
  • uptake analysis
  • diagnostics

Published Papers (2 papers)

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Review

24 pages, 5088 KiB  
Review
Smart Platinum Nanostructures: A Journey from Synthesis to Advanced Theranostic Applications
by Akash Kumar, Nabojit Das and Raja Gopal Rayavarapu
J. Nanotheranostics 2023, 4(3), 384-407; https://doi.org/10.3390/jnt4030017 - 10 Aug 2023
Viewed by 1344
Abstract
A significant paradigm shift has been observed in the past decade in the area of theranostics owing to the development of various isotropic and anisotropic metal nanostructures, simultaneous with improved imaging modalities. Platinum-based nanostructures are advancing in a plethora of clinical applications as [...] Read more.
A significant paradigm shift has been observed in the past decade in the area of theranostics owing to the development of various isotropic and anisotropic metal nanostructures, simultaneous with improved imaging modalities. Platinum-based nanostructures are advancing in a plethora of clinical applications as theranostics tools owing to their unique behavior concerning their size, shape, and surface chemistry at the nanoscale regime. Platinum nanostructures are optically active and provide significant potential to the field of theranostics by simplifying diagnosis and therapeutics, thus providing key solutions through nano-enabled technologies. The review emphasizes the potential of platinum nanostructures that have immense potential in vitro and in vivo scenarios as nanocarriers. Still, their potential in terms of photothermal active agents has not been well explored or reported. Nanotheranostics has emerged as a platform where various noble metal nanoparticles are effectively efficient as photothermal agents in bringing precision to therapy and diagnostics. Platinum, as an antioxidant and a stable nanocarrier, will enable them to act as photosensitizers when conjugated to affinity molecules and plays a key role in efficient treatment and diagnosis. The review envisions bringing together the possibilities of the safe-by-design synthesis of platinum nanostructures and their potential role in both in vitro and in vivo applications. A roadmap describing the challenges, pitfalls, and possibilities of influencing platinum nanostructures to overcome the existing biological/targeting barriers is elaborated. This review provides a literature survey on platinum nanostructures in theranostics, providing novel strategies in bio-imaging, diagnostics, and nanomedicine. Full article
(This article belongs to the Special Issue Role of Nano-Bio Interaction for Nanotheranostic Applications)
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32 pages, 5440 KiB  
Review
Emerging Trends in the Application of Green Synthesized Biocompatible ZnO Nanoparticles for Translational Paradigm in Cancer Therapy
by Shaikh Sheeran Naser, Basab Ghosh, Faizan Zarreen Simnani, Dibyangshee Singh, Anmol Choudhury, Aditya Nandi, Adrija Sinha, Ealisha Jha, Pritam Kumar Panda, Mrutyunjay Suar and Suresh K. Verma
J. Nanotheranostics 2023, 4(3), 248-279; https://doi.org/10.3390/jnt4030012 - 01 Jul 2023
Cited by 13 | Viewed by 2984
Abstract
Zinc oxide nanomaterials have been the cynosure of this decade because of their immense potential in different biomedical applications. It includes their usage in the prognosis and treatment of different infectious and cellular diseases, owing to their peculiar physiochemical properties such as variable [...] Read more.
Zinc oxide nanomaterials have been the cynosure of this decade because of their immense potential in different biomedical applications. It includes their usage in the prognosis and treatment of different infectious and cellular diseases, owing to their peculiar physiochemical properties such as variable shape, size, and surface charge etc. Increasing demand and usage of the ZnO nanomaterials raise concerns about their cellular and molecular toxicity and their biocompatibility with human cells. This review comprehensively details their physiochemical properties for usage in biomedical applications. Furthermore, the toxicological concerns of ZnO nanomaterials with different types of cellular systems have been reviewed. Moreover, the biomedical and biocompatible efficacy of ZnO nanomaterials for cancer specific pathways has been discussed. This review offers insights into the current scenario of ZnO nanomaterials usage and signifies their potential future extension usage on different types of biomedical and environmental applications. Full article
(This article belongs to the Special Issue Role of Nano-Bio Interaction for Nanotheranostic Applications)
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