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Bioactive Coatings and Surfaces for Medical Applications
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Bioactive Coatings and Surfaces for Medical Applications

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 3561

Special Issue Editors

Dr. Zhou Ye

E-Mail Website
Guest Editor
Faculty of Dentistry, The University of Hong Kong, Hong Kong, China
Interests: biomaterials; supramolecular materials; drug delivery; surface and interfaces; biomineralization; antimicrobial; bone regeneration; diabetes
Dr. Ting Sang

E-Mail Website
Guest Editor
School of Stomatology, Nanchang University, Nanchang, China
Interests: dental materials; antimicrobial coating; antimicrobial peptides; silver nanoparticle; peri-implant infections; bacteria adhesion

Special Issue Information

Dear Colleagues,

The interfaces formed between the medical device/implant's surfaces and the surrounding biological environments highly determine their bioactivities in medical applications. Modifications to the surface topography and compositions could alter the biomaterials' properties and/or introduce new bioactivities, including biocompatibility, mechanical properties, wear resistance, antimicrobial/antifouling activity, angiogenesis, and osteogenesis. With the emerging needs to solve the recurring healthcare problems or improve the performance of existing medical devices, researchers have been developing new chemical or physical strategies to form coatings and surface nanostructures leveraging their biofunctions in preventing infections, promoting tissue regeneration, regulating immunology, etc.

This Special Issue is dedicated to the basic and applied studies on the topics of bioactive coatings and surfaces and their interactions with biological systems, including, but not limited to, new synthesis routes, material fabrication techniques, characterization methodologies, in vitro and in vivo assessments, mechanistic studies, and translational studies. Original research articles and reviews related to these topics are welcome to be submitted to this Special Issue. We believe that the broad readership of the Journal of Functional Biomaterials would convey your research to scientists and clinicians in the fields of biomaterials, tissue engineering, biochemistry, microbiology, dentistry, orthopedics, dermatology, oncology, etc.

Dr. Zhou Ye
Dr. Ting Sang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coatings
  • surface nanostructures
  • interfaces
  • bioactivity
  • biomaterials
  • implants

Published Papers (2 papers)

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Research

14 pages, 6460 KiB  
Article
Green Ultrasound-Assisted Synthesis of Surface-Decorated Nanoparticles of Fe3O4 with Au and Ag: Study of the Antifungal and Antibacterial Activity
by Álvaro de Jesús Ruíz-Baltazar, Harald Norbert Böhnel, Daniel Larrañaga Ordaz, José Antonio Cervantes-Chávez, Néstor Méndez-Lozano and Simón Yobanny Reyes-López
J. Funct. Biomater. 2023, 14(6), 304; https://doi.org/10.3390/jfb14060304 - 01 Jun 2023
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Abstract
This work proposes a sonochemical biosynthesis of magnetoplasmonic nanostructures of Fe3O4 decorated with Au and Ag. The magnetoplasmonic systems, such as Fe3O4 and Fe3O4-Ag, were characterized structurally and magnetically. The structural characterizations reveal [...] Read more.
This work proposes a sonochemical biosynthesis of magnetoplasmonic nanostructures of Fe3O4 decorated with Au and Ag. The magnetoplasmonic systems, such as Fe3O4 and Fe3O4-Ag, were characterized structurally and magnetically. The structural characterizations reveal the magnetite structures as the primary phase. Noble metals, such as Au and Ag, are present in the sample, resulting in a structure-decorated type. The magnetic measurements indicate the superparamagnetic behavior of the Fe3O4-Ag and Fe3O4-Au nanostructures. The characterizations were carried out by X-ray diffraction and scanning electron microscopy. Complementarily, antibacterial and antifungal assays were carried out to evaluate the potential properties and future applications in biomedicine. Full article
(This article belongs to the Special Issue Bioactive Coatings and Surfaces for Medical Applications)
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15 pages, 6576 KiB  
Article
Developing a Novel Enamel Adhesive with Amorphous Calcium Phosphate and Silver Nanoparticles to Prevent Demineralization during Orthodontic Treatment
by Ao Jia, Pei Wang, Fei Tong, Ziqiang Chen, Yunyun Deng, Haiyan Yao, Lianguo Wang, Yifan Liu and Hongshan Ge
J. Funct. Biomater. 2023, 14(2), 77; https://doi.org/10.3390/jfb14020077 - 29 Jan 2023
Cited by 1 | Viewed by 1585
Abstract
During fixed orthodontic treatment, white spot lesions are prevalent issues associated with cariogenic bacteria. This study aims to construct an orthodontic adhesive containing nanoparticles of amorphous calcium phosphate-polydopamine-Ag (NPA) fillers to combat white spot lesions. The NPA fillers were prepared and characterized by [...] Read more.
During fixed orthodontic treatment, white spot lesions are prevalent issues associated with cariogenic bacteria. This study aims to construct an orthodontic adhesive containing nanoparticles of amorphous calcium phosphate-polydopamine-Ag (NPA) fillers to combat white spot lesions. The NPA fillers were prepared and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The biocompatibility of the fillers was evaluated. A colony counting test evaluated the antibacterial property of the fillers against Streptococcus mutans (S. mutans). NPA fillers were mixed with orthodontic adhesive (Transbond XT) at different weight ratios (0, 0.1, 0.2, 0.3, and 0.5 wt.%). The shear bond strength and antibacterial properties were then further investigated. The results showed that NPA was prepared successfully, with good antibacterial properties. The cell survival rate of all groups of fillers was higher than 70%, showing good biocompatibility. Moreover, the shear bond strength of the orthodontic adhesive with 0.2 wt.% NPA fillers was 11.89 ± 1.27 MPa, meeting the minimal clinical bond strength requirements of 7.8 MPa. Furthermore, the orthodontic adhesive resin blocks and the extract displayed good antibacterial properties, with the number of colonies decreasing significantly (p < 0.001). Taken together, we think that an orthodontic adhesive with NPA may have a good application potential for the prevention and treatment of white spot lesions. Full article
(This article belongs to the Special Issue Bioactive Coatings and Surfaces for Medical Applications)
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