Latest in Keratoconus: Diagnosis, Pathophysiology and Genetics

Dear Colleagues,

Keratoconus is a common condition that affects the cornea, and despite its increasing prevalence, the cause of keratoconus is largely unknown. There are many clinical gaps regarding keratoconus in terms of subclinical detection, clarifying its disease stage and identifying which features should be used to predict its progression. These gaps impact a clinician’s decision-making process for keratoconus disease management.

The disease has recently benefited from improvements in molecular genetics, corneal imaging, and novel therapeutic insights. This Special Issue of the Journal of Clinical & Translational Ophthalmology entitled “Latest in Keratoconus: Diagnosis, Pathophysiology and Genetics” will detail the latest developments in understanding keratoconus and the recent advances in corneal imaging leading to early and more accurate diagnosis, and better-targeted patient follow-up. The contributors to this Issue will also focus on machine learning algorithms and advanced genetic techniques to identify the features that define early subclinical keratoconus that are currently refractory, as well as identify a series of features that are involved in (a) disease staging and (b) risk of progression of keratoconus.

Dr. Srujana Sahebjada
Guest Editor

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