Special Issue "Clinical Updates on Graves' Disease"
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".
Deadline for manuscript submissions: closed (15 November 2023) | Viewed by 243
Special Issue Editors
Interests: thyroid autoimmunity; Graves' disease; Hashimoto's thyroiditis; Graves' orbitopathy; thyroid cancer; pituitary gland; iodine
Interests: thyroid autoimmunity; Graves' disease; Hashimoto's thyroiditis; Vitamina D; Selenium; obesity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Graves’ disease (GD) is a common autoimmune disorder in which antibodies stimulating the thyrotropin receptors (TSHR-Ab) cause hyperthyroidism and goiter. The most relevant extrathyroid manifestation is Graves’ orbitopathy (GO), which is severe in almost 5% of cases and potentially sight-threatening. In most cases, anti-thyroid drug treatment represents the primary therapeutic approach but carries a high risk of hyperthyroidism relapse after discontinuation. Alternative treatments are radioiodine and thyroidectomy, which invariably determine hypothyroidism. Glucocorticoids represent a milestone but imperfect treatment for GO. Thus, a crucial topic of research is the improvement of GD and GO management. Strategies might include the early identification of those patients at higher risk of refractory hyperthyroidism or relapse that would benefit from a definitive approach. Importantly, novel discoveries in the pathogenesis of GD and GO paved the way for new therapies, targeting TSHR-Ab, IGF-1R, or modulating the immune response. We invite investigators working in this field of research to submit original research articles or reviews on the most recent advancements in this topic.
Prof. Dr. Maria Laura Tanda
Dr. Daniela Gallo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Graves’ disease
- Graves’ orbitopathy
- glucocorticoids
- target therapies
