Management of Diabetes in Cardiovascular Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".
Deadline for manuscript submissions: 20 August 2024 | Viewed by 1920
Special Issue Editor
Interests: type 2 diabetes; obesity; metabolic surgery; precision diabetology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We cordially invite you to participate as an author in this Special Issue of JCM on “Management of Diabetes in Cardiovascular Diseases”.
Multiple cardiovascular (CV) risk factors, such as hypertension, dyslipidemia, obesity and inflammation, often coexist in individuals with type 2 diabetes (T2DM). Atherosclerotic cardiovascular disease (ASCVD) and heart failure (HF) are leading causes of morbidity and mortality for these patients. Intensive glycemic control reduces the microvascular complications of T2DM, but it does not provide a clear beneficial effect on ASCVD or HF. In recent years, several glucose-lowering drugs (GLDs) from two therapeutic families, GLP-1 receptor agonists and sodium-glucose co-transporter type 2 inhibitors, have shown a reduction in CV and renal morbidity and mortality in patients with T2DM and CV disease. A comprehensive approach to CV reduction in T2DM should include these GLDs, irrespective of the glycemic control or metformin use, and at the same level as other drugs with CV or renal protection, such as statins, PCSK-9 inhibitors, bempedoic acid, icosapent ethyl, ezetimibe, acetylsalicylic acid, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers or finerenone. Other important elements of the multifactorial intensification of therapy in patients with T2DM and CV disease include a healthy lifestyle, weight loss in overweight patients, and deprescription of those drugs without CV benefit and, in some cases, metabolic surgery.
In summary, we have multiple tools to change the natural history of patients with T2DM and ASCVD or HF at present. We look forward to receiving your submissions to this Special Issue.
Dr. Juan José Gorgojo-Martínez
Guest Editor
Manuscript Submission Information
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Keywords
- type 2 diabetes
- cardiovascular disease
- lifestyle
- SGLT-2 inhibitors
- GLP-1 receptor agonists
- weight-loss drugs
- metabolic surgery.