Special Issue "Current Advances on Molecular & Clinical Oncology: Diagnosis, Management and Treatment of the Malignant Causative Genes"
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 4883
Interests: photo catalysis; membrane reactor; nanocatalyst; plasmonics nanoparticle; smart polymer
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Interests: pediatric oncology; haematology; pediatrics and neonatology; pediatrics cardiology; regenerative medicines; fetal cardiology; cosmetic surgery; pediatric asthma
Interests: research and diagnostic of radio-immunology (dosage of GH, IGF-1 and other endocrine dependences); thalassemia; tumor; immune haematology; blood transfusion
Although laboratory and clinical cancer research need to be closely linked and observations should be at the basic level are often remain removed from medical applications. Not only that early diagnosis of clinical cancer and their treatment management are also not properly taken care of. In this special issue we will focus on current advancement on the cancer treatment not only by clinical means but also in genetic level by manipulating the causative genes. So we mostly focus on how we identify inherited/causative cancer, and current knowledge of the most frequent and clinically important forms of clinical cancers. The concept of identifying causative genes emerged from the recognized of its young onset in families more than 60 years ago. The last three decades has seen the causative genes for most of the high-penetrant cancer syndromes with Mendelian inheritance identified, and their genetic epidemiology is now being described. Its multidisciplinary approach allows us to keep up-to-date with developments in their own as well as related fields. Crucial to such descriptions is how to identify pathogenic variants of the causative genes, which are instrumental to demonstrate their associations with early stage of the disease. From the starting point of identifying the genes causing cancer with very high complexity of treatment challenges of is the aim of this special issue. Recent advancement of drug discovery developments in the field of small cancer molecule targeted agents have led to much interest in combining these clinical research with treatment management will also be covered in this special issue. Apart from different genetic variants with lower risk to develop cancer, and their interactions with other genes and environment, we will also welcome the contributions on this perceived future opportunities and challenges in the development of this exciting area of oncological research and study.
Prof. Dr. Sudip Chakraborty
Dr. Gianpiero Aromolo
Dr. Giampaolo De Luca
Manuscript Submission Information
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- Molecularly targeted drugs
- Genetic epidemiology
- Early detection
- New technologies
- Cancer biology
- Clinical trials
- Cancer causative genes