Special Issue "Advances and Challenges in Spine Surgery"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 25 February 2024 | Viewed by 239

Special Issue Editors

Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Interests: spinal cord injury; low back pain; disc degeneration; minimally invasive spine surgery; spinal deformity; traumatic brain injury
Prof. Dr. Micheal Wang
Guest Editor
Department of Neurosurgery and Rehab Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA
Interests: minimally invasive spine surgery; awake spine surgery; ERAS (enhanced recovery after surgery); endoscopic spine surgery; spinal deformity; robotics; spinal cord injury biomarkers

Special Issue Information

Dear Colleagues,

Spine surgery has undergone tremendous advancement in the past several decades. We have gained a much deeper understanding of how to approach the spine while minimizing trauma to the normal tissue, how to stabilize the spine respecting the natural spine biomechanics, and how to maintain or restore optimal spine alignment when performing reconstructive spine surgeries. Significant technological advancements have reshaped how we treat spinal ailments. Modern segmental fixation and hardware technologies have allowed more secure and stable spinal fixation. The refinement of spinal navigation has helped spine surgeons place hardware more safely and with greater accuracy. The innovations in biological material technology have greatly facilitated successful bony healing and fusion after spine surgery.

We have started to gain a better understanding of the pathophysiology of the origin of back pain. In addition, we have also begun to understand the molecular changes occurring after spinal cord injury and the basic molecular process involved in spinal axon regeneration. 

There are still plenty of challenges facing us in spine surgery. How to decrease the rate of disc degeneration and minimize discogenic back pain, how to accurately determine the etiologies of various kinds of back pain, how to preserve spinal motion and physiological flexibility with spinal instrumentation, how to avoid adjacent level disease with spinal fusion, and how to minimize delayed iatrogenic spinal instability with spinal decompression are all examples of the issues facing spine surgeons on a daily basis. In addition, spinal cord injury remains one of the most challenging and unresolved issues in modern neuroscience. We have yet to find an effective treatment to reverse the functional loss for patients suffering from severe spinal cord injury. 

The current Special Issue will present the most up-to-date advances in spine surgery, discuss our new understanding of the pathophysiology of the spine and spinal cord biology, and introduce the challenges that remain to be solved in spine surgery.

Dr. Yi Lu
Prof. Dr. Micheal Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • spinal surgery
  • low back pain
  • spinal biomechanics
  • spinal surgical anatomy
  • minimally invasive spine surgery
  • spinal deformity
  • spinal cord injury
  • spinal trauma
  • spinal oncology

Published Papers

This special issue is now open for submission.
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