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Special Issue "Aortic Diseases and Complications: Diagnosis and Treatment"

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Prof. Dr. Alexis Jacquier
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Department of Radiology, Timone Hospital, Assistance Publique-Hôpitaux de Marseille, 13005 Marseille, France
Interests: aortic diseases; aortic dissection; aortic aneurysm; complications; coronary artery disease; transcatheter aortic valve implantation

Special Issue Information

Dear Colleagues,

This Special Issue, "Aortic Diseases and Complications: Diagnosis and Treatment", presents the latest research on the diagnosis and treatmeny management of aortic diseases and their complications. The Special Issue covers key themes, including aortic aneurysms, dissections, and valve disorders, and focuses on the latest diagnostic techniques, imaging post-processing, and open surgical or endovascular interventions. The papers also discuss the challenges of managing aortic diseases in high-risk Marfan syndrome and associated diseases.

The research in this Special Issue emphasizes the need for early detection and intervention to prevent complications and improve patient outcomes. The papers presented here contribute significantly to the advancement of knowledge in the field of aortic diseases and provide valuable insights for clinicians and researchers alike.

With this Special Issue, we want to provide a platform for scientists to publish their new scientific findings in the area of aortic diseases and complications to further progress this important topic in the field of diagnostics and therapy.

Prof. Dr. Alexis Jacquier
Guest Editor

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Keywords

aortic diseases
diagnosis
treatment
complications
management
high-risk patients
outcomes

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Research

Open AccessArticle

In Marfan Syndrome and Related Diseases, STABILISE Technique Should Be Used with Care: Results from a Volumetric Comparative Study of Endovascular Treatment for Aortic Dissection

and

J. Clin. Med. 2023, 12(13), 4378; https://doi.org/10.3390/jcm12134378 - 29 Jun 2023

Viewed by 359

Abstract

Objectives: Aortic dissection in patients with Marfan and related syndromes (HTAD) is a serious pathology whose treatment by thoracic endovascular repair (TEVAR) is still under debate. The aim of this study was to assess the results of the TEVAR for aortic dissection in patients with HTAD as compared to a young population without HTAD. Methods: The study received the proper ethical oversight. We performed an observational exposed (confirmed HTAD) vs. non-exposed (<65 years old) study of TEVAR-treated patients. The preoperative, 1 year, and last available CT scans were analyzed. The thoracic and abdominal aortic diameters, aortic length, and volumes were measured. The entry tears and false lumen (FL) status were assessed. The demographic, clinical, and anatomic data were collected during the follow-up. Results: Between 2011 and 2021, 17 patients were included in the HTAD group and 22 in the non-HTAD group. At 1 year, the whole aortic volume increased by +21.2% in the HTAD group and by +0.2% the non-HTAD groups, p = 0.005. An increase in the whole aortic volume > 10% was observed in ten cases (58.8%) in the HTAD group and in five cases (22.7%) in the non-HTAD group (p = 0.022). FL thrombosis was achieved in nine cases (52.9%) in the HTAD group vs. twenty (90.9%) cases in the non-HTAD group (p < 0.01). The risk factors for unfavorable anatomical evolution were male gender and the STABILISE technique. With a linear model, we observed a significantly different aortic volume evolution between the two groups (p < 0.01) with the STABILISE technique; this statistical difference was not found in the TEVAR subgroup. In the HTAD patients, there was a significant difference in the total aortic volume evolution progression between the patients treated with the STABILISE technique and the patients treated with TEVAR (+160.1 ± 52.3% vs. +47 ± 22.5%, p < 0.01 and +189.5 ± 92.5% vs. +58.6 ± 34.8%, p < 0.01 at 1 year and at the end of follow-up, respectively). Conclusions: TEVAR in the HTAD patients seemed to be associated with poorer anatomical outcomes at 1 year. This result was strongly related to the STABILISE technique which should be considered with care in these specific patients. Full article

(This article belongs to the Special Issue Aortic Diseases and Complications: Diagnosis and Treatment)

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Special Issue "Aortic Diseases and Complications: Diagnosis and Treatment"

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