Dear Colleagues,

It was a pleasure to collaborate as a Guest Editor in the Special Issue “Cardiovascular Disease in 2021 and beyond—What Have We Learned and How Do We Move On?” for the Journal of Clinical Medicine, which was published in 2021 (https://www.mdpi.com/journal/jcm/special_issues/Cardiovascular_Disease_What_We_Have_Learned_and_How_We_Move_On). Fortunately, participation was high, with 12 manuscripts including original research and reviews.

Our goal now is to launch a second edition of the Special Issue, titled “Cardiovascular Disease in 2021 and beyond—What Have We Learned and How Do We Move On? - Volume II: For 2023 and Beyond”. This last decade has witnessed major advances in the management of pre-hospital patients. One example is electrocardiogram-based telemedicine as a cornerstone in pre-hospital triage; other efforts have also been made to triage patients in the pre-hospital setting in order to expedite triage, diagnosis and treatment. Future research should focus on the possibilities for enhancing the early diagnosis and treatment of these patients to improve outcomes.

Furthermore, device therapies such as transcatheter aortic valve replacement and mitral clips emerged nearly 20 years ago and changed the landscape of structural heart intervention cardiology. These procedures have rapidly transitioned from an innovative procedure to the standard of care. Trends in the utilization of percutaneous devices in the cath-lab have evolved, starting from their occasional use just a few decades ago to exponential usage.

This Special Issue aims to focus on both the pre-hospital settings of cardiovascular patients and trends and updates in cutting-edge structural heart disease. Accordingly, this section of the journal that I was kindly invited to edit may include original clinical studies, data-based original analyses and literature reviews (systematic reviews and meta-analysis).

I believe that this unique combination, which covers pre-hospital settings and in-hospital advanced technology, will be of interest and extremely valuable to readers.

Dr. David Planer
Dr. Gabby Elbaz-Greener
Dr. Ronny Alcalai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• pre-hospital care
• hospital care
• emergency intervention
• interventional cardiology
• pulmonary emboli
• congestive heart failure
• TAVR
• mitral clip