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Chronic Obstructive Pulmonary Diseases (COPD): Diagnosis, Treatment and Rehabilitation
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Chronic Obstructive Pulmonary Diseases (COPD): Diagnosis, Treatment and Rehabilitation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Rehabilitation".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 3853

Special Issue Editor

Dr. Marc Spielmanns

E-Mail Website
Guest Editor
Priv.-Doz. Dr. med.
1. Department for Pulmonary Medicine and Sleep Medicine, Zürcher RehaZentren, Klinik Wald, 8636 Wald, Swit-zerland
2. Department for Pulmonary Medicine, Faculty of Health, University Witten-Herdecke, 58455 Witten, Germany
Interests: rehabilitation; COPD; pulmonary rehabilitation; exercise training in pulmonary diseases

Special Issue Information

Dear Colleagues,

COPD has gained considerable importance in recent years, not least because it is now the third leading cause of death worldwide. The burden of COPD is expected to rise in the coming years, and medical professionals have become aware of its huge impact on patients. Due to the enormous gain in knowledge in the context of scientific study results, the therapy of COPD has changed from a purely symptomatic treatment in the direction of an intervention influencing the course of the disease. New scientific knowledge is the only way to win the battle against COPD.

With this Special Issue, we want to provide a platform for scientists to publish their new scientific findings in the field of COPD to further progress this important topic in the field of diagnostics, therapy, and rehabilitation. Clinical trial results should include both pharmacologic and non-pharmacologic approaches. Novel treatment strategies including precision medicine are welcome. The aim is to optimize patient outcomes in COPD ultimately through knowledge gain.

Original papers are especially desired, but also reviews and interesting case reports. We look forward to your contributions and hope for an interesting and relevant compilation of publications on COPD.

Dr. Marc Spielmanns
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COPD
  • pulmonary rehabilitation
  • pharmacologic treatment
  • diagnostic
  • exercise training
  • therapy

Published Papers (2 papers)

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Research

11 pages, 1117 KiB  
Article
Clinical Effects of Pulmonary Rehabilitation in Very Old Patients with COPD
by Marc Spielmanns, Sofia-Theresia Schulze, Erhan Guenes, Katarzyna Pekacka-Falkowska, Wolfram Windisch and Anna Maria Pekacka-Egli
J. Clin. Med. 2023, 12(7), 2513; https://doi.org/10.3390/jcm12072513 - 27 Mar 2023
Cited by 2 | Viewed by 1944
Abstract
Background: Pulmonary rehabilitation (PR) improves physical and mental performance as well as quality of life in patients with chronic obstructive pulmonary disease (COPD). However, data on outcomes in very old patients are insufficient. We analyzed whether the elderly with COPD benefit in a [...] Read more.
Background: Pulmonary rehabilitation (PR) improves physical and mental performance as well as quality of life in patients with chronic obstructive pulmonary disease (COPD). However, data on outcomes in very old patients are insufficient. We analyzed whether the elderly with COPD benefit in a similar way to younger patients from participation in an inpatient PR according to the assessments usually collected. Methods: Data from 3173 patients with COPD were retrospectively analyzed. Patients were referred to PR at the Zurich RehaZentren, Switzerland, between January 2013 and December 2019. PR was performed 6 days per week with an average duration of 18.85 days. Functional Independence Measurement (FIM), Feeling Thermometer (FT), and 6-Minute Walk Test (6MWT) were recorded on admission and discharge. Results: In all age groups, the 6MWT and FT improved significantly. FIM results also showed a significant increase. The results of the different age groups showed no significant differences in percentage improvements according to the assessments that were considered. Conclusions: All patient groups with COPD, even the oldest (>85 years), benefited from PR regardless of their age and according to the assessments. Prospective studies are needed to support this hypothesis. Full article
(This article belongs to the Special Issue Chronic Obstructive Pulmonary Diseases (COPD): Diagnosis, Treatment and Rehabilitation)
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16 pages, 1261 KiB  
Article
Alteration of the Respiratory Microbiome in Hospitalized Patients with Asthma–COPD Overlap during and after an Exacerbation
by Ahmad R. Alsayed, Anas Abed, Yazun Bashir Jarrar, Farhan Alshammari, Bushra Alshammari, Iman A. Basheti and Malek Zihlif
J. Clin. Med. 2023, 12(6), 2118; https://doi.org/10.3390/jcm12062118 - 08 Mar 2023
Cited by 8 | Viewed by 1549
Abstract
The immediate aim of this study was to comparatively examine the bacterial respiratory microbiome of patients in a stable state and during an exacerbation of asthma–COPD (chronic obstructive pulmonary disease) overlap (ACO). This prospective observational study took place in Jordan between 1 September [...] Read more.
The immediate aim of this study was to comparatively examine the bacterial respiratory microbiome of patients in a stable state and during an exacerbation of asthma–COPD (chronic obstructive pulmonary disease) overlap (ACO). This prospective observational study took place in Jordan between 1 September 2021 and 30 April 2022. Sputum samples from patients with recognized ACO were acquired within 48 h of the exacerbation onset and again at 3 weeks following the exacerbation. The next-generation sequencing Illumina MiSeq was employed and uncovered significantly high bacterial diversity in the sputa. The results showed a significant decrease in the taxonomic richness in the sputum samples collected during the exacerbation episodes compared with those collected from patients in a stable state (p = 0.008), with an increase in the taxonomic evenness (p < 0.005). This change in the composition of the airway bacterial community suggests that the replacement of a significant portion of the airway microbiome with certain microorganisms may play a role in the decrease in microbial diversity observed during an ACO exacerbation. Greater knowledge of this link could allow for a more focused administration of antibiotics, especially during exacerbations, improving clinical efficacy and patient outcomes. Full article
(This article belongs to the Special Issue Chronic Obstructive Pulmonary Diseases (COPD): Diagnosis, Treatment and Rehabilitation)
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