Clinical Advances in Aortic Disease and Revascularization

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Vascular Medicine".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 862

Special Issue Editor

Guest Editor
Department of Endovascular and Vascular Surgery, Brandenburg Medical School Theodor Fontane, Brandenburg University Hospital, Brandenburg an der Havel, Germany
Interests: probabilistic programming; neural networks; intravascular ultrasound; quality of life

Special Issue Information

Dear Colleagues,

Although the management of aortic diseases (AD) has undergone evolutionary and fundamental changes in recent decades due to the establishment of more or less complex endovascular procedures and has become much safer and less invasive, many issues remain and new problems have emerged. There is still limited evidence regarding the differential indications for the (non-operative, endovascular or open-surgical) treatment of aneurysms, penetrating ulcers, dissections, etc. Demographic changes have led to much older patients with a range of comorbidities, often with limited operability, and new questions, such as those of the patient’s quality of life vs. overall survival, have arisen. Major randomized controlled trials investigating the outcomes of endovascular vs. non-operative vs. open-surgical treatment no longer fully reflect the realities of today, and new, more real-world-focusing approaches are needed, including registry data, artificial intelligence, Bayes statistics or other prediction models enabling clinicians to judge with empathy and intuition, supported by patient-individual prognosis. Moreover, new contrast media and radiation-sparing technology, such as intravascular ultrasound, image fusion and virtual reality, will rapidly bring about new perspectives for the treatment of difficult anatomies. Last but not least, the molecular base of ADs will fundamentally change our point of view, since the course of AD has to be associated with a specific etiology rather than with the morphology (i.e., diameter) alone.

Dr. Andrej Udelnow
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • aortic disease
  • aortic aneurysm
  • endovascular aortic repair
  • atherosclerosis
  • aortic dissections
  • overall survival
  • quality of life
  • intravascular ultrasound

Published Papers (1 paper)

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11 pages, 1277 KiB  
Oversizing Consideration of Proximal Stent Graft in Hemodynamically Stable and Unstable Patients Undergoing Emergent Endovascular Aortic Repair
by Yuhan Qi, Chengxin Weng, Ding Yuan, Tiehao Wang, Yukui Ma, Yi Yang, Jichun Zhao and Bin Huang
J. Clin. Med. 2023, 12(23), 7500; - 04 Dec 2023
Viewed by 727
Consideration for oversizing the proximal stent graft is suggested in endovascular aortic repair. However, a special recommendation for the proximal oversizing ratio (OSR) in patients with ruptured abdominal aortic aneurysm (rAAA) is ambiguous. This study aims to evaluate the effect of different degrees [...] Read more.
Consideration for oversizing the proximal stent graft is suggested in endovascular aortic repair. However, a special recommendation for the proximal oversizing ratio (OSR) in patients with ruptured abdominal aortic aneurysm (rAAA) is ambiguous. This study aims to evaluate the effect of different degrees of the proximal oversizing ratio (OSR) on risk of type IA endoleak (TIAEL) in hemodynamically stable and unstable patients with rAAA undergoing emergency endovascular aortic repair (EVAR). Our study included 134 rAAA patients undergoing emergent EVAR, and we did not observe a significant association between hemodynamic instability and risk of T1AEL (HR 3.89, 95%CI 0.40–37.75, p = 0.24). All three T1AELs in the hemodynamically unstable subgroup were observed in patients with OSR ≤ 30%, but no significant difference was found regarding T1AEL between patients with OSR > 30% and OSR ≤ 30% (0.00% vs. 11.11%, p = 0.19). As for hemodynamically stable patients, OSR > 20% was associated with a significantly decreased risk of T1AEL (HR 0.03, 95%CI 0.01–0.53, p = 0.016). In conclusion, a proximal OSR > 20% is associated with a decreased risk of T1AEL in hemodynamically stable patients, while an OSR > 30% did not add an additional advantage of lowering the risk of T1AEL in hemodynamically unstable patients. Full article
(This article belongs to the Special Issue Clinical Advances in Aortic Disease and Revascularization)
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