Special Issue "Updates on Anesthesia in General Surgery"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Anesthesiology".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 568

Special Issue Editors

Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Justus Liebig University of Giessen, 35392 Giessen, Germany
Interests: sepsis; inflammation; biomarker; hemodynamic; fungal infections; intensive care medicine
Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Justus Liebig University of Giessen, 35392 Giessen, Germany
Interests: sepsis; resuscitation; critical care medicine; mechanical ventilation; intensive care medicine; airway management; cardiopulmonary resuscitation; CPR; emergency management; emergency treatment

Special Issue Information

Dear Colleagues,

In recent years, the practice of anesthesiology has significantly changed. In addition to the application of safe anesthesia and analgesia during general surgery, anesthesiologists’ responsibilities also include the preoperative patient evaluation and improvement, as well as postoperative care. Furthermore, the increasing number of patients with significant comorbidities poses considerable challenges for anesthetists.

The identification and management of patient- and procedure-related risk factors play pivotal roles in daily clinical practice. Novel surgical techniques in general surgery and changing patient collectives have led to considerable challenges for anesthesiologists and intensivists.

Therefore, the use of risk stratification methods and modern anesthetic procedures is key to successful patient care.

In this Special Issue of the Journal of Clinical Medicine, we encourage the submission of original and review papers concerning topics relevant to anesthesia, intensive care and pain therapy in patients undergoing general surgery, with the aim of helping anesthesiologists and intensivists to apply the most appropriate patient treatments.

Dr. Christian Koch
Dr. Emmanuel Schneck
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anesthesiology
  • analgesic
  • anesthetic
  • intensive care
  • pain therapy
  • pre-operative patient evaluation and improvement
  • post-operative care

Published Papers (1 paper)

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Research

Article
Potentials of Acetylcholinesterase and Butyrylcholinesterase Alterations in On-Pump Coronary Artery Bypass Surgery in Postoperative Delirium: An Observational Trial
J. Clin. Med. 2023, 12(16), 5245; https://doi.org/10.3390/jcm12165245 - 11 Aug 2023
Viewed by 392
Abstract
Cardiac surgery is regularly associated with postoperative delirium (POD), affected by neuro-inflammation and changes in cholinergic activity. Therefore, this prospective observational study aimed to evaluate whether pre- and perioperative changes in blood acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity were associated with POD development [...] Read more.
Cardiac surgery is regularly associated with postoperative delirium (POD), affected by neuro-inflammation and changes in cholinergic activity. Therefore, this prospective observational study aimed to evaluate whether pre- and perioperative changes in blood acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity were associated with POD development in patients undergoing isolated elective coronary artery bypass graft (CABG) surgery. It included 93 patients. Pre- and postoperative blood AChE and BChE activities were measured with photometric rapid-point-of-care-testing. The Intensive Care Delirium Screening Checklist and the Confusion Assessment Method for the Intensive Care Unit were used to screen patients for POD. POD developed in 20 patients (21.5%), who were older (p = 0.003), had higher EuroSCOREs (p ≤ 0.001), and had longer intensive care unit stays (p < 0.001). On postoperative day one, BChE activity decreased from preoperative values more in patients with (31.9%) than without (23.7%) POD (group difference p = 0.002). Applying a cutoff of ≥32.0% for BChE activity changes, receiver operating characteristic analysis demonstrated a moderate prediction capability for POD (area under the curve = 0.72, p = 0.002). The risk of developing POD was 4.31 times higher with a BChE activity change of ≥32.0% (p = 0.010). Monitoring the pre- to postoperative reduction in BChE activity might be a clinically practicable biomarker for detecting patients at risk of developing POD after CABG surgery. Full article
(This article belongs to the Special Issue Updates on Anesthesia in General Surgery)
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