Special Issue "Plant Bio-Factories for the Production of High-Value Metabolites, Recombinant Proteins, and Other Biologics"

A special issue of International Journal of Plant Biology (ISSN 2037-0164).

Deadline for manuscript submissions: 31 December 2023 | Viewed by 594

Special Issue Editor

Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand
Interests: plant biotechnology; molecular farming; recombinant proteins; subunit vaccine; plant metabolic engineering; plant cell cultures

Special Issue Information

Dear Colleagues,

The demand for recombinant proteins in terms of quality, quantity, and diversity is increasing steadily, attracting global attention for the development of new recombinant protein production technologies and the engineering of conventional established expression systems based on bacteria or mammalian cell cultures. Over the past three decades, plants have been used for the production of economically valuable, biologically active non-native proteins or biopharmaceuticals. The technology has grown and advanced tremendously in recent years. Many biopharmaceuticals, including vaccines, antibodies, diagnostic reagents, blood substitutes, industrial enzymes, and various metabolites, are produced in plants, some of which are in the preclinical and clinical pipeline. Progress around the approval of the plant-based biopharmaceutical ZMapp by the FDA and Medicago’s COVID-19 vaccine by Health Canada has displayed the potential of a plant platform for biopharmaceutical production, especially during emergency situations. This proposed Special Issue in the International Journal of Plant Biology will comprehensively present the current research and highlight the feasibility of plant-based platforms for the production of metabolites, recombinant proteins, or other high-value biologics, with special emphasis on the most recent advances in the field, as well as on the challenges that remain for the future. The related subjects of modern plant biotechnology, including metabolic engineering, metabolite expression, and synthetic biology, will also be included in the Special Issue. We welcome review articles, research articles, and short communications that address this mission and encourage scientific contributions discussing the current trends related to this promising area from both academia and industry.

Dr. Balamurugan Shanmugaraj
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Plant Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • molecular farming
  • recombinant proteins
  • bioreactors
  • plant-based platforms
  • algae biopharming
  • in vitro cell cultures
  • metabolic engineering
  • techno-economics

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Author: Julia Bally
Affiliation: Centre for Tropical Crops and Biocommodities, QUT
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