Special Issue "Natural Bioactive Compounds against Microorganisms: Sources and Mechanism of Action"
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 7176
For some time now, natural compounds have been becoming increasingly important in the fight against microorganisms and infectious diseases. As certain antibiotics and other anti-infective substances, though in use for a long time, have been deemed no longer adequate in their effectiveness against microorganisms, natural compounds, whose use is often only derived from traditional experimentation, have taken on an increasingly important role thanks to their capability, effectiveness and tolerability. The role of this Special Issue is to highlight their mechanism of action, often little known or not known at all, through experimental or mixed computational/experimental methods that often provide an atomistic mechanism for the clarification and elucidation of the macroscopically observed experimental behavior. Computational methods, in fact, if combined with experimental ones, can help to outline a mechanism of action. Especially in this pandemic period, the role of these substances, often coming from plants but also from other sources, has been widely re-evaluated. In fact, the phytoextracts can count on the synergistic action of a variety of compounds that actually amplify their properties and prevent microorganisms from being able to weaken or cancel their therapeutic properties with a bypass action.
This Special Issue welcomes original research and review articles in the field, with a focus on but not limited to the molecular and mechanistic basis of the natural compound activity against microorganisms.
I look forward to receiving your contributions.
Dr. Mattia Falconi
Manuscript Submission Information
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- natural compounds
- mechanism of action
- anti-infective activity
- experimental tests
- computational studies
- atomistic machinery